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Jakinibs for the treatment of immune dysregulation in patients with gain-of-function signal transducer and activator of transcription 1 (STAT1) or STAT3 mutations.
Forbes, Lisa R; Vogel, Tiphanie P; Cooper, Megan A; Castro-Wagner, Johana; Schussler, Edith; Weinacht, Katja G; Plant, Ashley S; Su, Helen C; Allenspach, Eric J; Slatter, Mary; Abinun, Mario; Lilic, Desa; Cunningham-Rundles, Charlotte; Eckstein, Olive; Olbrich, Peter; Guillerman, R Paul; Patel, Niraj C; Demirdag, Yesim Y; Zerbe, Christa; Freeman, Alexandra F; Holland, Steven M; Szabolcs, Paul; Gennery, Andrew; Torgerson, Troy R; Milner, Joshua D; Leiding, Jennifer W.
Affiliation
  • Forbes LR; Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, Baylor College of Medicine, Houston, Tex; Center for Human Immunobiology, Texas Children's Hospital, Houston, Tex. Electronic address: lisa.forbes@bcm.edu.
  • Vogel TP; Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, Baylor College of Medicine, Houston, Tex; Center for Human Immunobiology, Texas Children's Hospital, Houston, Tex.
  • Cooper MA; Department of Pediatrics, Division of Rheumatology, Washington University, St Louis, Mo.
  • Castro-Wagner J; Division of Allergy and Immunology, Department of Pediatrics, University of South Florida, St Petersburg, Fla.
  • Schussler E; Division of Allergy and Immunology and Department of Medicine and Pediatrics, The Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Weinacht KG; Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford School of Medicine, Stanford, Calif.
  • Plant AS; Department of Pediatric Oncology, Children's Hospital of Orange County, Orange, Calif.
  • Su HC; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
  • Allenspach EJ; Division of Rheumatology, Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, Wash.
  • Slatter M; Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation and Primary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle upon Tyne University, United Kingdom.
  • Abinun M; Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation and Primary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle upon Tyne University, United Kingdom.
  • Lilic D; Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation and Primary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle upon Tyne University, United Kingdom.
  • Cunningham-Rundles C; Division of Allergy and Immunology and Department of Medicine and Pediatrics, The Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Eckstein O; Department of Hematology and Oncology, Texas Children's Cancer Center, Houston, Tex.
  • Olbrich P; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md; Department of Pediatric Infectious Diseases and Immunopathologies, Institute of Biomedicine Seville (IBiS), University Hospital Virgen del Rocio, Seville, Spain.
  • Guillerman RP; Department of Pediatric Radiology, Texas Children's Hospital and Department of Radiology, Baylor College of Medicine, Houston, Tex.
  • Patel NC; Department of Pediatrics, Section of Infectious Disease and Immunology, Levine Children's Hospital, Atrium Health, Charlotte, NC.
  • Demirdag YY; Department of Pediatrics, Division of Pediatric Allergy and Immunology, College of Physcians and Surgeons of Columbia Univeristy, New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY.
  • Zerbe C; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
  • Freeman AF; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
  • Holland SM; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
  • Szabolcs P; Division of Blood and Marrow Transplantation and Cellular Therapies, University of Pittsburgh, Pittsburgh, Pa.
  • Gennery A; Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation and Primary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle upon Tyne University, United Kingdom.
  • Torgerson TR; Division of Rheumatology, Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, Wash.
  • Milner JD; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
  • Leiding JW; Division of Allergy and Immunology, Department of Pediatrics, University of South Florida, St Petersburg, Fla; Cancer and Blood Disorders Institute, Johns Hopkins-All Children's Hospital, St Petersburg, Fla. Electronic address: jleiding@health.usf.edu.
J Allergy Clin Immunol ; 142(5): 1665-1669, 2018 11.
Article in En | MEDLINE | ID: mdl-30092289
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: STAT1 Transcription Factor / STAT3 Transcription Factor / Janus Kinases / Immunologic Deficiency Syndromes Type of study: Clinical_trials Limits: Adolescent / Adult / Child / Female / Humans / Male Language: En Journal: J Allergy Clin Immunol Year: 2018 Document type: Article Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: STAT1 Transcription Factor / STAT3 Transcription Factor / Janus Kinases / Immunologic Deficiency Syndromes Type of study: Clinical_trials Limits: Adolescent / Adult / Child / Female / Humans / Male Language: En Journal: J Allergy Clin Immunol Year: 2018 Document type: Article Country of publication: Estados Unidos