High tuberculosis transmission rate in children with nursery exposure to undetected pulmonary tuberculosis.
Int J Tuberc Lung Dis
; 22(9): 1031-1036, 2018 09 01.
Article
in En
| MEDLINE
| ID: mdl-30092868
ABSTRACT
SETTING:
Nursery for newborns in Busan, Republic of Korea.OBJECTIVE:
To evaluate tuberculosis (TB) transmission from a health care worker with active pulmonary TB to neonatal contacts.DESIGN:
For the first investigation, infants who had been in the nursery 3 months before the index patient was diagnosed with pulmonary TB were enrolled. After a child who had stayed in the nursery 10 months before the diagnosis of the index patient was diagnosed with tuberculous meningitis, a second contact investigation was conducted.RESULTS:
Respectively 315 and 1334 children participated in the first and second investigations. The mean age of the contacts was 66.3 days; the rate of latent tuberculous infection (LTBI) at the first investigation was 42.5% (134/315). Only one infant had an abnormal chest X-ray, and was thought to have pulmonary TB. In the second investigation, the mean age of the participants was 17.6 months. The proportion of children with LTBI was 18.7% (249/1334).CONCLUSIONS:
The LTBI rate in the present study was much higher than that estimated from other contact investigations. To minimise the risk of nosocomial TB transmission to neonates, screening and management of TB in health care workers should be strengthened.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tuberculosis, Pulmonary
/
Cross Infection
/
Infectious Disease Transmission, Professional-to-Patient
/
Nurseries, Hospital
/
Nurses
Type of study:
Etiology_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
Country/Region as subject:
Asia
Language:
En
Journal:
Int J Tuberc Lung Dis
Year:
2018
Document type:
Article