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PP-22 promotes autophagy and apoptosis in the nasopharyngeal carcinoma cell line CNE-2 by inducing endoplasmic reticulum stress, downregulating STAT3 signaling, and modulating the MAPK pathway.
Tan, Gui-Xiang; Wang, Xin-Ning; Tang, Yun-Yun; Cen, Wan-Jing; Li, Zhen-Hua; Wang, Guo-Cai; Jiang, Jian-Wei; Wang, Xi-Cheng.
Affiliation
  • Tan GX; Department of Oncology, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
  • Wang XN; School of Nursing, Guangdong Pharmaceutical University, Guangzhou, China.
  • Tang YY; Department of Gastroenterology, People's Hospital of Qingyuan, Guangdong, China.
  • Cen WJ; Department of Oncology, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
  • Li ZH; Department of Oncology, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
  • Wang GC; Department of Stomatology, Guangzhou Development District Hospital, Guangzhou, China.
  • Jiang JW; Translation Research Institute, Jinan University, Guangzhou, China.
  • Wang XC; Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guangzhou, China.
J Cell Physiol ; 234(3): 2618-2630, 2019 03.
Article in En | MEDLINE | ID: mdl-30191969
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Saponins / Autophagy / Apoptosis / Endoplasmic Reticulum Stress Limits: Humans Language: En Journal: J Cell Physiol Year: 2019 Document type: Article Affiliation country: China Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Saponins / Autophagy / Apoptosis / Endoplasmic Reticulum Stress Limits: Humans Language: En Journal: J Cell Physiol Year: 2019 Document type: Article Affiliation country: China Country of publication: Estados Unidos