Invasive Curvularia Infection in Pediatric Patients With Hematologic Malignancy Identified by Fungal Sequencing.
J Pediatric Infect Dis Soc
; 8(1): 87-91, 2019 Mar 28.
Article
in En
| MEDLINE
| ID: mdl-30265347
ABSTRACT
Curvularia is a saprophytic dematiaceous mold and a rare human pathogen. Here, we report three severely immunocompromised pediatric patients who developed invasive Curvularia infection. Diagnosis was achieved or confirmed in all cases by fungal ribosome sequencing, which hastened species identification and targeted treatment for the patients reported. There are no treatment guidelines for invasive Curvularia infection, though we report three patients who were cured of their infection through a combination of surgical resection and various anti-fungal therapies, indicating a relatively low virulence and good prognosis in comparison to other angioinvasive molds.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ascomycota
/
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
/
Immunocompromised Host
/
Dermatomycoses
/
Precursor Cell Lymphoblastic Leukemia-Lymphoma
/
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Type of study:
Diagnostic_studies
/
Guideline
/
Prognostic_studies
Limits:
Child
/
Female
/
Humans
/
Male
Language:
En
Journal:
J Pediatric Infect Dis Soc
Year:
2019
Document type:
Article