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An autoimmune disease variant of IgG1 modulates B cell activation and differentiation.
Chen, Xiangjun; Sun, Xiaolin; Yang, Wei; Yang, Bing; Zhao, Xiaozhen; Chen, Shuting; He, Lili; Chen, Hui; Yang, Changmei; Xiao, Le; Chang, Zai; Guo, Jianping; He, Jing; Zhang, Fuping; Zheng, Fang; Hu, Zhibin; Yang, Zhiyong; Lou, Jizhong; Zheng, Wenjie; Qi, Hai; Xu, Chenqi; Zhang, Hong; Shan, Hongying; Zhou, Xu-Jie; Wang, Qingwen; Shi, Yi; Lai, Luhua; Li, Zhanguo; Liu, Wanli.
Affiliation
  • Chen X; Ministry of Education Key Laboratory of Protein Sciences, Center for Life Sciences, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Institute for Immunology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Sun X; Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing Key Laboratory for Rheumatism and Immune Diagnosis (BZ0135), Peking-Tsinghua Center for Life Sciences, State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100044, China.
  • Yang W; School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Yang B; Ministry of Education Key Laboratory of Protein Sciences, Center for Life Sciences, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Institute for Immunology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Zhao X; Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing Key Laboratory for Rheumatism and Immune Diagnosis (BZ0135), Peking-Tsinghua Center for Life Sciences, State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100044, China.
  • Chen S; Ministry of Education Key Laboratory of Protein Sciences, Center for Life Sciences, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Institute for Immunology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • He L; Ministry of Education Key Laboratory of Protein Sciences, Center for Life Sciences, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Institute for Immunology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Chen H; Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
  • Yang C; Ministry of Education Key Laboratory of Protein Sciences, Center for Life Sciences, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Institute for Immunology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Xiao L; Ministry of Education Key Laboratory of Protein Sciences, Center for Life Sciences, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Institute for Immunology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Chang Z; School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Guo J; Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing Key Laboratory for Rheumatism and Immune Diagnosis (BZ0135), Peking-Tsinghua Center for Life Sciences, State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100044, China.
  • He J; Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing Key Laboratory for Rheumatism and Immune Diagnosis (BZ0135), Peking-Tsinghua Center for Life Sciences, State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100044, China.
  • Zhang F; Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
  • Zheng F; Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Hu Z; Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
  • Yang Z; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Lou J; Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
  • Zheng W; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
  • Qi H; Tsinghua-Peking Center for Life Sciences, Laboratory of Dynamic Immunobiology, School of Medicine, Tsinghua University, Beijing 100084, China.
  • Xu C; State Key Laboratory of Molecular Biology, Shanghai Science Research Center, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China.
  • Zhang H; Renal Division, Peking University First Hospital, Peking University Institute of Nephrology, Key Laboratory of Renal Disease, Ministry of Health of China, Beijing 100034, China.
  • Shan H; Department of Rheumatism and Immunology, Peking University Shenzhen Hospital, Shenzhen 518036, China.
  • Zhou XJ; Renal Division, Peking University First Hospital, Peking University Institute of Nephrology, Key Laboratory of Renal Disease, Ministry of Health of China, Beijing 100034, China.
  • Wang Q; Department of Rheumatism and Immunology, Peking University Shenzhen Hospital, Shenzhen 518036, China.
  • Shi Y; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100101, China.
  • Lai L; Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, China.
  • Li Z; BNLMS, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, and Peking-Tsinghua Center for Life Sciences at College of Chemistry and Molecular Engineering, Center for Quantitative Biology, Peking University, Beijing 100871, China.
  • Liu W; Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing Key Laboratory for Rheumatism and Immune Diagnosis (BZ0135), Peking-Tsinghua Center for Life Sciences, State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100044, China. liulab@tsingh
Science ; 362(6415): 700-705, 2018 11 09.
Article in En | MEDLINE | ID: mdl-30287618
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / Lymphocyte Activation / Cell Differentiation / Lupus Erythematosus, Systemic Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Science Year: 2018 Document type: Article Affiliation country: China Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / Lymphocyte Activation / Cell Differentiation / Lupus Erythematosus, Systemic Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Science Year: 2018 Document type: Article Affiliation country: China Country of publication: Estados Unidos