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MNK1 inhibitor CGP57380 overcomes mTOR inhibitor-induced activation of eIF4E: the mechanism of synergic killing of human T-ALL cells.
Huang, Xian-Bo; Yang, Chun-Mei; Han, Qing-Mei; Ye, Xiu-Jin; Lei, Wen; Qian, Wen-Bin.
Affiliation
  • Huang XB; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, China.
  • Yang CM; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, China.
  • Han QM; Malignant Lymphoma Diagnosis and Therapy Center, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, China.
  • Ye XJ; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, China.
  • Lei W; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, China. yxjsunny@163.com.
  • Qian WB; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, China.
Acta Pharmacol Sin ; 39(12): 1894-1901, 2018 Dec.
Article in En | MEDLINE | ID: mdl-30297804
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Purines / Protein Serine-Threonine Kinases / Eukaryotic Initiation Factor-4E / Intracellular Signaling Peptides and Proteins / Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Aniline Compounds / Antineoplastic Agents Limits: Humans Language: En Journal: Acta Pharmacol Sin Journal subject: FARMACOLOGIA Year: 2018 Document type: Article Affiliation country: China Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Purines / Protein Serine-Threonine Kinases / Eukaryotic Initiation Factor-4E / Intracellular Signaling Peptides and Proteins / Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Aniline Compounds / Antineoplastic Agents Limits: Humans Language: En Journal: Acta Pharmacol Sin Journal subject: FARMACOLOGIA Year: 2018 Document type: Article Affiliation country: China Country of publication: Estados Unidos