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Engineered SH2 domains with tailored specificities and enhanced affinities for phosphoproteome analysis.
Veggiani, Gianluca; Huang, Haiming; Yates, Bradley P; Tong, Jiefei; Kaneko, Tomonori; Joshi, Rakesh; Li, Shawn S C; Moran, Michael F; Gish, Gerald; Sidhu, Sachdev S.
Affiliation
  • Veggiani G; Department of Biochemistry, University of Toronto, Toronto, Ontario, M5S 1A8, Canada.
  • Huang H; Donnelly Centre for Cellular and Biomolecular Research, Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, M5S3E1, Canada.
  • Yates BP; Department of Biochemistry, University of Toronto, Toronto, Ontario, M5S 1A8, Canada.
  • Tong J; Donnelly Centre for Cellular and Biomolecular Research, Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, M5S3E1, Canada.
  • Kaneko T; Department of Biochemistry, University of Toronto, Toronto, Ontario, M5S 1A8, Canada.
  • Joshi R; Donnelly Centre for Cellular and Biomolecular Research, Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, M5S3E1, Canada.
  • Li SSC; Program in Molecular Structure and Function, The Hospital for Sick Children, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, M5G 0A4, Canada.
  • Moran MF; Department of Biochemistry, Siebens-Drake Medical Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, N6A 5C1, Canada.
  • Gish G; Department of Biochemistry, Siebens-Drake Medical Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, N6A 5C1, Canada.
  • Sidhu SS; Department of Biochemistry, Siebens-Drake Medical Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, N6A 5C1, Canada.
Protein Sci ; 28(2): 403-413, 2019 02.
Article in En | MEDLINE | ID: mdl-30431205
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphoproteins / Protein Engineering / Src Homology Domains / Proteome Limits: Humans Language: En Journal: Protein Sci Journal subject: BIOQUIMICA Year: 2019 Document type: Article Affiliation country: Canadá Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphoproteins / Protein Engineering / Src Homology Domains / Proteome Limits: Humans Language: En Journal: Protein Sci Journal subject: BIOQUIMICA Year: 2019 Document type: Article Affiliation country: Canadá Country of publication: Estados Unidos