Relative equivalence of CNS safety (FOB) assessment outcomes in male and female Wistar-Han and Sprague-Dawley rats.

Gauvin, David V; Dalton, Jill A; Harter, Marci L; Holdsworth, David; May, Jonelle; Tapp, Rachel; Zimmermann, Zachary J; Kilgus, Quinn; Baird, Theodore J

Gauvin, David V; Dalton, Jill A; Harter, Marci L; Holdsworth, David; May, Jonelle; Tapp, Rachel; Zimmermann, Zachary J; Kilgus, Quinn; Baird, Theodore J.

Affiliation

Gauvin DV; Neurobehavioral Sciences Department, United States. Electronic address: david.gauvin@crl.com.
Dalton JA; Safety Pharmacology Department, United States.
Harter ML; Safety Pharmacology Department, United States.
Holdsworth D; Safety Pharmacology Department, United States.
May J; Safety Pharmacology Department, United States.
Tapp R; Neurobehavioral Sciences Department, United States.
Zimmermann ZJ; Neurobehavioral Sciences Department, United States.
Kilgus Q; Safety Pharmacology Department, United States.
Baird TJ; Drug Safety Assessment, United States.

J Pharmacol Toxicol Methods ; 95: 2-11, 2019.

Article in En | MEDLINE | ID: mdl-30476622

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rats / Central Nervous System / Toxicity Tests / Models, Animal / Drug-Related Side Effects and Adverse Reactions Type of study: Guideline / Prognostic_studies Limits: Animals Country/Region as subject: America do norte Language: En Journal: J Pharmacol Toxicol Methods Journal subject: FARMACOLOGIA / TOXICOLOGIA Year: 2019 Document type: Article Country of publication: Estados Unidos

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