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Changes in the serum metabolite profile correlate with decreased brain gray matter volume in moderate-to-heavy drinking young adults.
Heikkinen, Noora; Kärkkäinen, Olli; Laukkanen, Eila; Kekkonen, Virve; Kaarre, Outi; Kivimäki, Petri; Könönen, Mervi; Velagapudi, Vidya; Nandania, Jatin; Lehto, Soili M; Niskanen, Eini; Vanninen, Ritva; Tolmunen, Tommi.
Affiliation
  • Heikkinen N; Department of Clinical Radiology, Kuopio University Hospital, Puijonlaaksontie 2, 70210 Kuopio, Finland; Doctoral Programme of Clinical Research, School of Medicine, University of Eastern Finland, Yliopistonranta 1, 70210 Kuopio, Finland. Electronic address: noora.heikkinen@uef.fi.
  • Kärkkäinen O; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Yliopistonranta 1, 70210 Kuopio, Finland; Department of Forensic Psychiatry, University of Eastern Finland, Niuvanniemi Hospital, Niuvankuja 65, 70240 Kuopio, Finland.
  • Laukkanen E; Department of Adolescent Psychiatry, Kuopio University Hospital, Puijonlaaksontie 2, 70210 Kuopio, Finland; Department of Psychiatry, School of Medicine, University of Eastern Finland, Yliopistonranta 1, 70210 Kuopio, Finland.
  • Kekkonen V; Department of Adolescent Psychiatry, Kuopio University Hospital, Puijonlaaksontie 2, 70210 Kuopio, Finland.
  • Kaarre O; Doctoral Programme of Clinical Research, School of Medicine, University of Eastern Finland, Yliopistonranta 1, 70210 Kuopio, Finland; Department of Adolescent Psychiatry, Kuopio University Hospital, Puijonlaaksontie 2, 70210 Kuopio, Finland.
  • Kivimäki P; Doctoral Programme of Clinical Research, School of Medicine, University of Eastern Finland, Yliopistonranta 1, 70210 Kuopio, Finland.
  • Könönen M; Department of Clinical Radiology, Kuopio University Hospital, Puijonlaaksontie 2, 70210 Kuopio, Finland; Department of Clinical Neurophysiology, Kuopio University Hospital, Puijonlaaksontie 2, 70210 Kuopio, Finland.
  • Velagapudi V; Metabolomics Unit, Institute for Molecular Medicine Finland FIMM, University of Helsinki, Tukholmankatu 8, 00270 Helsinki, Finland.
  • Nandania J; Metabolomics Unit, Institute for Molecular Medicine Finland FIMM, University of Helsinki, Tukholmankatu 8, 00270 Helsinki, Finland.
  • Lehto SM; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Haartmaninkatu 8, 00014 Helsinki, Finland; Institute of Clinical Medicine, University of Eastern Finland, Yliopistonranta 1, 70210 Kuopio, Finland; Department of Psychiatry, Kuopio University Hospital, Puijonlaakso
  • Niskanen E; Department of Applied Physics, University of Eastern Finland, Yliopistonranta 1, 70210 Kuopio, Finland.
  • Vanninen R; Department of Clinical Radiology, Kuopio University Hospital, Puijonlaaksontie 2, 70210 Kuopio, Finland.
  • Tolmunen T; Department of Psychiatry, School of Medicine, University of Eastern Finland, Yliopistonranta 1, 70210 Kuopio, Finland; Department of Clinical Neurophysiology, Kuopio University Hospital, Puijonlaaksontie 2, 70210 Kuopio, Finland.
Alcohol ; 75: 89-97, 2019 03.
Article in En | MEDLINE | ID: mdl-30513444
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alcohol Drinking / Cerebral Cortex / Metabolomics / Gray Matter Type of study: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Adolescent / Adult / Female / Humans / Male Language: En Journal: Alcohol Journal subject: TRANSTORNOS RELACIONADOS COM SUBSTANCIAS Year: 2019 Document type: Article Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alcohol Drinking / Cerebral Cortex / Metabolomics / Gray Matter Type of study: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Adolescent / Adult / Female / Humans / Male Language: En Journal: Alcohol Journal subject: TRANSTORNOS RELACIONADOS COM SUBSTANCIAS Year: 2019 Document type: Article Country of publication: Estados Unidos