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Prevalence and type of artefact with spectral domain optical coherence tomography macular ganglion cell imaging in glaucoma surveillance.
Awadalla, Mona S; Fitzgerald, Jude; Andrew, Nicholas H; Zhou, Tiger; Marshall, Henry; Qassim, Ayub; Hassall, Mark; Casson, Robert J; Graham, Stuart L; Healey, Paul R; Agar, Ashish; Galanopoulos, Anna; Phipps, Simon; Chappell, Angela; Landers, John; Craig, Jamie E.
Affiliation
  • Awadalla MS; Flinders University, Department of Ophthalmology, South Australia, Australia.
  • Fitzgerald J; Flinders University, Department of Ophthalmology, South Australia, Australia.
  • Andrew NH; Flinders University, Department of Ophthalmology, South Australia, Australia.
  • Zhou T; Flinders University, Department of Ophthalmology, South Australia, Australia.
  • Marshall H; Flinders University, Department of Ophthalmology, South Australia, Australia.
  • Qassim A; Flinders University, Department of Ophthalmology, South Australia, Australia.
  • Hassall M; Flinders University, Department of Ophthalmology, South Australia, Australia.
  • Casson RJ; University of Adelaide, Discipline of Ophthalmology & Visual Sciences, Adelaide, Australia.
  • Graham SL; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
  • Healey PR; University of Sydney Discipline of Ophthalmology, Sydney, Australia.
  • Agar A; Centre for Vision Research, Westmead Institute for Medical Research, University of Sydney, Sydney, Australia.
  • Galanopoulos A; Marsden Eye Specialists, Sydney, Australia.
  • Phipps S; Department of Ophthalmology, Prince of Wales Hospital, University of New South Wales, Sydney, Australia.
  • Chappell A; University of Adelaide, Discipline of Ophthalmology & Visual Sciences, Adelaide, Australia.
  • Landers J; Goodwood Eye Centre, Millswood, South Australia.
  • Craig JE; Flinders University, Department of Ophthalmology, South Australia, Australia.
PLoS One ; 13(12): e0206684, 2018.
Article in En | MEDLINE | ID: mdl-30517101
ABSTRACT

PURPOSE:

The ganglion cell analysis (GCA) of the CIRRUSTM HD-OCT (Carl Zeiss, Meditec; Dublin, CA) provides measurement of the macular ganglion cell-inner plexiform layer (GCIPL) thickness. This study determined the frequency of scan artefacts and errors in GCIPL imaging in individuals undergoing HD-OCT surveillance for glaucoma.

METHOD:

A total of 1439 eyes from 721 subjects enrolled in a prospective study assessing predictors of glaucoma progression underwent macular GCIPL imaging with the CIRRUS HD-OCT at recruitment. The prevalence of acquisition errors, segmentation errors, and co-morbid macular pathology was determined.

RESULTS:

A total of 87 (6.0%) of the 1439 scans had either acquisition errors, segmentation artefacts, or other macular pathology. The most common co-morbid macular pathology was epiretinal membrane in 2.2% of eyes.

CONCLUSION:

The macular GCIPL scan was artefact free in 94% of eyes. However, epiretinal membrane and high myopia can cause scan artefact and should be considered when interpreting the results.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinal Ganglion Cells / Glaucoma / Tomography, Optical Coherence / Diagnostic Errors Type of study: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies / Screening_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2018 Document type: Article Affiliation country: Australia
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinal Ganglion Cells / Glaucoma / Tomography, Optical Coherence / Diagnostic Errors Type of study: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies / Screening_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2018 Document type: Article Affiliation country: Australia