The Transient Receptor Potential Channel, Vanilloid 5, Induces Chondrocyte Apoptosis via Ca2+ CaMKII-Dependent MAPK and Akt/ mTOR Pathways in a Rat Osteoarthritis Model.

Wei, Yingliang; Jin, Zhaofeng; Zhang, He; Piao, Shang; Lu, Jinghan; Bai, Lunhao

Wei, Yingliang; Jin, Zhaofeng; Zhang, He; Piao, Shang; Lu, Jinghan; Bai, Lunhao.

Affiliation

Wei Y; Department of Orthopedic Surgery, ShengJing Hospital, China Medical University, ShenYang, China.
Jin Z; Department of Orthopedic Surgery, Fushun Hospital of Chinese Medicine, Fu Shun, China.
Zhang H; Department of Orthopedic Surgery, ShengJing Hospital, China Medical University, ShenYang, China.
Piao S; Department of Orthopedic Surgery, ShengJing Hospital, China Medical University, ShenYang, China.
Lu J; Department of Orthopedic Surgery, ShengJing Hospital, China Medical University, ShenYang, China.
Bai L; Department of Orthopedic Surgery, ShengJing Hospital, China Medical University, ShenYang, Chinabailh@sj-hospital.org.

Cell Physiol Biochem ; 51(5): 2309-2323, 2018.

Article in En | MEDLINE | ID: mdl-30537737

Subject(s)
Key words

Ca2+; Chondrocyte apoptosis; Osteoarthritis; P-CaMKII; TRPV5

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Calcium Channels / Signal Transduction / Calcium / Apoptosis / Chondrocytes / TRPV Cation Channels Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cell Physiol Biochem Journal subject: BIOQUIMICA / FARMACOLOGIA Year: 2018 Document type: Article Affiliation country: China Country of publication: Alemania

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