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Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers.
Tokatlian, Talar; Read, Benjamin J; Jones, Christopher A; Kulp, Daniel W; Menis, Sergey; Chang, Jason Y H; Steichen, Jon M; Kumari, Sudha; Allen, Joel D; Dane, Eric L; Liguori, Alessia; Sangesland, Maya; Lingwood, Daniel; Crispin, Max; Schief, William R; Irvine, Darrell J.
Affiliation
  • Tokatlian T; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Read BJ; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Jones CA; Health Sciences and Technology, Harvard University and Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Kulp DW; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Menis S; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104, USA.
  • Chang JYH; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Steichen JM; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Kumari S; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Allen JD; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Dane EL; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Liguori A; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Sangesland M; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Lingwood D; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Crispin M; Biological Sciences and the Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK.
  • Schief WR; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Irvine DJ; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
Science ; 363(6427): 649-654, 2019 02 08.
Article in En | MEDLINE | ID: mdl-30573546
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides / HIV Envelope Protein gp120 / HIV Infections / AIDS Vaccines / Germinal Center / Immunity, Innate / Antibody Formation Type of study: Prognostic_studies Limits: Animals Language: En Journal: Science Year: 2019 Document type: Article Affiliation country: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides / HIV Envelope Protein gp120 / HIV Infections / AIDS Vaccines / Germinal Center / Immunity, Innate / Antibody Formation Type of study: Prognostic_studies Limits: Animals Language: En Journal: Science Year: 2019 Document type: Article Affiliation country: Estados Unidos