The depolymerase activity of MCAK shows a graded response to Aurora B kinase phosphorylation through allosteric regulation.

McHugh, Toni; Zou, Juan; Volkov, Vladimir A; Bertin, Aurélie; Talapatra, Sandeep K; Rappsilber, Juri; Dogterom, Marileen; Welburn, Julie P I

McHugh, Toni; Zou, Juan; Volkov, Vladimir A; Bertin, Aurélie; Talapatra, Sandeep K; Rappsilber, Juri; Dogterom, Marileen; Welburn, Julie P I.

Affiliation

McHugh T; Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, UK.
Zou J; Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, UK.
Volkov VA; Department of Bionanoscience, Faculty of Applied Sciences, Delft University of Technology, Delft 2629, The Netherlands.
Bertin A; Laboratoire Physico Chimie Curie, Institut Curie, PSL Research University, CNRS UMR168, 75005 Paris, France.
Talapatra SK; Sorbonne Universités, UPMC University Paris 06, 75005 Paris, France.
Rappsilber J; Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, UK.
Dogterom M; Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, UK.
Welburn JPI; Chair of Bioanalytics, Institute of Biotechnology, Technische Universität Berlin, Berlin 10623, Germany.

J Cell Sci ; 132(4)2019 01 14.

Article in En | MEDLINE | ID: mdl-30578316

Subject(s)
Key words

Aurora B; MCAK; Microtubules; Phosphorylation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Kinesins / Kinetochores / Aurora Kinase B / Microtubules Limits: Animals / Humans Language: En Journal: J Cell Sci Year: 2019 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido

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