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A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates.
Bornholdt, Zachary A; Herbert, Andrew S; Mire, Chad E; He, Shihua; Cross, Robert W; Wec, Anna Z; Abelson, Dafna M; Geisbert, Joan B; James, Rebekah M; Rahim, Md Niaz; Zhu, Wenjun; Borisevich, Viktoriya; Banadyga, Logan; Gunn, Bronwyn M; Agans, Krystle N; Wirchnianski, Ariel S; Goodwin, Eileen; Tierney, Kevin; Shestowsky, William S; Bohorov, Ognian; Bohorova, Natasha; Velasco, Jesus; Ailor, Eric; Kim, Do; Pauly, Michael H; Whaley, Kevin J; Alter, Galit; Walker, Laura M; Chandran, Kartik; Zeitlin, Larry; Qiu, Xiangguo; Geisbert, Thomas W; Dye, John M.
Affiliation
  • Bornholdt ZA; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
  • Herbert AS; United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD, USA.
  • Mire CE; Department of Microbiology and Immunology, Galveston National Laboratory, University of Texas Medical Branch at Galveston, Galveston, TX, USA.
  • He S; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.
  • Cross RW; Department of Microbiology and Immunology, Galveston National Laboratory, University of Texas Medical Branch at Galveston, Galveston, TX, USA.
  • Wec AZ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Abelson DM; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
  • Geisbert JB; Department of Microbiology and Immunology, Galveston National Laboratory, University of Texas Medical Branch at Galveston, Galveston, TX, USA.
  • James RM; United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD, USA.
  • Rahim MN; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada.
  • Zhu W; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.
  • Borisevich V; Department of Microbiology and Immunology, Galveston National Laboratory, University of Texas Medical Branch at Galveston, Galveston, TX, USA.
  • Banadyga L; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.
  • Gunn BM; The Ragon Institute, Cambridge, MA, USA.
  • Agans KN; Department of Microbiology and Immunology, Galveston National Laboratory, University of Texas Medical Branch at Galveston, Galveston, TX, USA.
  • Wirchnianski AS; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Goodwin E; Adimab LLC, Lebanon, NH, USA.
  • Tierney K; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.
  • Shestowsky WS; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
  • Bohorov O; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
  • Bohorova N; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
  • Velasco J; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
  • Ailor E; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
  • Kim D; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
  • Pauly MH; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
  • Whaley KJ; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
  • Alter G; The Ragon Institute, Cambridge, MA, USA.
  • Walker LM; Adimab LLC, Lebanon, NH, USA.
  • Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Zeitlin L; Mapp Biopharmaceutical, Inc., San Diego, CA, USA. Electronic address: larry.zeitlin@mappbio.com.
  • Qiu X; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada. Electronic address: xiangguo.qiu@canada.ca.
  • Geisbert TW; Department of Microbiology and Immunology, Galveston National Laboratory, University of Texas Medical Branch at Galveston, Galveston, TX, USA. Electronic address: twgeisbe@utmb.edu.
  • Dye JM; United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD, USA. Electronic address: john.m.dye1.civ@mail.mil.
Cell Host Microbe ; 25(1): 49-58.e5, 2019 01 09.
Article in En | MEDLINE | ID: mdl-30629918

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hemorrhagic Fever, Ebola / Ebolavirus / Ferrets / Antibodies, Monoclonal / Antibodies, Viral Limits: Animals / Female / Humans / Male Language: En Journal: Cell Host Microbe Journal subject: MICROBIOLOGIA Year: 2019 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hemorrhagic Fever, Ebola / Ebolavirus / Ferrets / Antibodies, Monoclonal / Antibodies, Viral Limits: Animals / Female / Humans / Male Language: En Journal: Cell Host Microbe Journal subject: MICROBIOLOGIA Year: 2019 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos