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Aquilariaenes A-H, eight new diterpenoids from Chinese eaglewood.
Yang, Lin; Guo, Peiyi; Liu, Aijing; Sui, Songyang; Shi, Sha; Guo, Shunxing; Dai, Jungui.
Affiliation
  • Yang L; College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China. Electronic address: 15116995486@163.com.
  • Guo P; College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China.
  • Liu A; College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China.
  • Sui S; College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China.
  • Shi S; College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China.
  • Guo S; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China.
  • Dai J; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, CAMS Key Laboratory of Enzyme and Biocatalysis of Medicinal Natural Products, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China. Electronic address: jgda
Fitoterapia ; 133: 180-185, 2019 Mar.
Article in En | MEDLINE | ID: mdl-30659875
ABSTRACT
Aquilariaenes A-H (1-8), eight new diterpenoids and nor-diterpenoids (1-8) belonging to abietane or pimarane, were isolated from the petroleum ether extract of Chinese eaglewood. Their structures were elucidated on the basis of extensive spectroscopic methods including HRESIMS, IR, 1D and 2D NMR spectroscopic data analyses. Antidepressant activities of isolates for in vitro inhibition of serotonin and norepinephrine reuptake in rat brain synaptosomes were evaluated.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Synaptosomes / Thymelaeaceae / Diterpenes / Antidepressive Agents Limits: Animals Language: En Journal: Fitoterapia Year: 2019 Document type: Article Country of publication: HOLANDA / HOLLAND / NETHERLANDS / NL / PAISES BAJOS / THE NETHERLANDS
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Synaptosomes / Thymelaeaceae / Diterpenes / Antidepressive Agents Limits: Animals Language: En Journal: Fitoterapia Year: 2019 Document type: Article Country of publication: HOLANDA / HOLLAND / NETHERLANDS / NL / PAISES BAJOS / THE NETHERLANDS