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Capmatinib (INC280) Is Active Against Models of Non-Small Cell Lung Cancer and Other Cancer Types with Defined Mechanisms of MET Activation.
Baltschukat, Sabrina; Engstler, Barbara Schacher; Huang, Alan; Hao, Huai-Xiang; Tam, Angela; Wang, Hui Qin; Liang, Jinsheng; DiMare, Matthew T; Bhang, Hyo-Eun Carrie; Wang, Youzhen; Furet, Pascal; Sellers, William R; Hofmann, Francesco; Schoepfer, Joseph; Tiedt, Ralph.
Affiliation
  • Baltschukat S; Novartis Institutes for BioMedical Research, Oncology Disease Area, Basel, Switzerland.
  • Engstler BS; Novartis Institutes for BioMedical Research, Oncology Disease Area, Basel, Switzerland.
  • Huang A; Novartis Institutes for BioMedical Research, Oncology Disease Area, Cambridge, Massachusetts.
  • Hao HX; Novartis Institutes for BioMedical Research, Oncology Disease Area, Cambridge, Massachusetts.
  • Tam A; Novartis Institutes for BioMedical Research, Oncology Disease Area, Cambridge, Massachusetts.
  • Wang HQ; Novartis Institutes for BioMedical Research, Oncology Disease Area, Cambridge, Massachusetts.
  • Liang J; Novartis Institutes for BioMedical Research, Oncology Disease Area, Cambridge, Massachusetts.
  • DiMare MT; Novartis Institutes for BioMedical Research, Oncology Disease Area, Cambridge, Massachusetts.
  • Bhang HC; Novartis Institutes for BioMedical Research, Oncology Disease Area, Cambridge, Massachusetts.
  • Wang Y; Novartis Institutes for BioMedical Research, Oncology Disease Area, Cambridge, Massachusetts.
  • Furet P; Novartis Institutes for BioMedical Research, Global Discovery Chemistry, Basel, Switzerland.
  • Sellers WR; Novartis Institutes for BioMedical Research, Oncology Disease Area, Cambridge, Massachusetts.
  • Hofmann F; Novartis Institutes for BioMedical Research, Oncology Disease Area, Basel, Switzerland.
  • Schoepfer J; Novartis Institutes for BioMedical Research, Global Discovery Chemistry, Basel, Switzerland.
  • Tiedt R; Novartis Institutes for BioMedical Research, Oncology Disease Area, Basel, Switzerland. ralph.tiedt@novartis.com.
Clin Cancer Res ; 25(10): 3164-3175, 2019 05 15.
Article in En | MEDLINE | ID: mdl-30674502
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triazines / Carcinoma, Non-Small-Cell Lung / Proto-Oncogene Proteins c-met / Protein Kinase Inhibitors / Drug Evaluation, Preclinical / Imidazoles / Lung Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2019 Document type: Article Affiliation country: Suiza Country of publication: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triazines / Carcinoma, Non-Small-Cell Lung / Proto-Oncogene Proteins c-met / Protein Kinase Inhibitors / Drug Evaluation, Preclinical / Imidazoles / Lung Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2019 Document type: Article Affiliation country: Suiza Country of publication: Estados Unidos