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An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade.
Vuong, Lynda; Kouverianou, Eleni; Rooney, Claire M; McHugh, Brian J; Howie, Sarah E M; Gregory, Christopher D; Forbes, Stuart J; Henderson, Neil C; Zetterberg, Fredrik R; Nilsson, Ulf J; Leffler, Hakon; Ford, Paul; Pedersen, Anders; Gravelle, Lise; Tantawi, Susan; Schambye, Hans; Sethi, Tariq; MacKinnon, Alison C.
Affiliation
  • Vuong L; Department of Asthma, Allergy and Respiratory Science, King's College London, Guy's Hospital, London, United Kingdom.
  • Kouverianou E; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh Bioquarter, Edinburgh, United Kingdom.
  • Rooney CM; Department of Asthma, Allergy and Respiratory Science, King's College London, Guy's Hospital, London, United Kingdom.
  • McHugh BJ; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh Bioquarter, Edinburgh, United Kingdom.
  • Howie SEM; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh Bioquarter, Edinburgh, United Kingdom.
  • Gregory CD; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh Bioquarter, Edinburgh, United Kingdom.
  • Forbes SJ; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh Bioquarter, Edinburgh, United Kingdom.
  • Henderson NC; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh Bioquarter, Edinburgh, United Kingdom.
  • Zetterberg FR; Galecto Biotech, Copenhagen, Denmark.
  • Nilsson UJ; Department of Chemistry, Centre for Analysis and Synthesis, Lund University, Lund, Sweden.
  • Leffler H; Department of Laboratory Medicine, Section MIG, Lund University, Lund, Sweden.
  • Ford P; Galecto Biotech, Copenhagen, Denmark.
  • Pedersen A; Galecto Biotech, Copenhagen, Denmark.
  • Gravelle L; Galecto Biotech, Copenhagen, Denmark.
  • Tantawi S; Galecto Biotech, Copenhagen, Denmark.
  • Schambye H; Galecto Biotech, Copenhagen, Denmark.
  • Sethi T; Department of Asthma, Allergy and Respiratory Science, King's College London, Guy's Hospital, London, United Kingdom.
  • MacKinnon AC; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh Bioquarter, Edinburgh, United Kingdom. a.mackinnon@ed.ac.uk.
Cancer Res ; 79(7): 1480-1492, 2019 04 01.
Article in En | MEDLINE | ID: mdl-30674531

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Galectin 3 / Cell Proliferation / B7-H1 Antigen / Adenocarcinoma of Lung / Lung Neoplasms Limits: Animals / Female / Humans Language: En Journal: Cancer Res Year: 2019 Document type: Article Affiliation country: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Galectin 3 / Cell Proliferation / B7-H1 Antigen / Adenocarcinoma of Lung / Lung Neoplasms Limits: Animals / Female / Humans Language: En Journal: Cancer Res Year: 2019 Document type: Article Affiliation country: Reino Unido