Hepatitis A immunity in Yozgat, Turkey.
Ann Saudi Med
; 39(1): 37-41, 2019.
Article
in En
| MEDLINE
| ID: mdl-30712049
ABSTRACT
BACKGROUND:
Since routine immunization could change the epidemiological profile of hepatitis A virus (HAV) infection in the future, it is important to determine the baseline immunity to HAV across Turkey.OBJECTIVE:
The aim of this study was to determine the seroprevalence of hepatitis A among individuals 6 years of age and older in Yozgat, Turkey.DESIGN:
Cross-sectional.SETTING:
Community in central region of Turkey. PATIENTS ANDMETHODS:
Questionnaires and blood specimens were collected and the presence of hepatitis A IgG antibodies against hepatitis A virus was determined quantitatively by ELISA. MAIN OUTCOMEMEASURES:
The rates of hepatitis A immunity by age group. SAMPLE SIZE 1862.RESULTS:
Immunity to hepatitis A was 79.1% (n=1473). The mean (SD) age was 17.1 (14.7) years in the nonimmune group and 37.8 (19.5) years in the immune group (P less than .001), and immunity increased with age. No significant difference in immunity rate was detected between gen.ders in children and adults. The seropositivity rate for subjects ages 6-19 years was lower than in subjects aged 20-96 years (52.2% versus 93.9%; P less than .001).CONCLUSION:
A catch-up vaccination program is needed for persons aged 6-19 years in Yozgat.LIMITATIONS:
Single region data which can not be generalized. For this reason, a multi-centered study that can reflect the whole country is recommended. CONFLICT OF INTEREST None.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Vaccination
/
Hepatitis A Vaccines
/
Hepatitis A virus
/
Hepatitis A Antibodies
/
Hepatitis A
Type of study:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Asia
Language:
En
Journal:
Ann Saudi Med
Journal subject:
MEDICINA
Year:
2019
Document type:
Article