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The Special Pathogens Research Network: Enabling Research Readiness.
Kraft, Colleen S; Kortepeter, Mark G; Gordon, Bruce; Sauer, Lauren M; Shenoy, Erica S; Eiras, Daniel P; Larson, LuAnn; Garland, Jennifer A; Mehta, Aneesh K; Barrett, Kevin; Price, Connie S; Croyle, Caroline; West, Lauren R; Noren, Brooke; Kline, Susan; Arguinchona, Christa; Arguinchona, Henry; Grein, Jonathan D; Connally, Chad; McLellan, Susan; Risi, George F; Uyeki, Timothy M; Davey, Richard T; Schweinle, Jo Ellen; Schwedhelm, Michelle M; Harvey, Melissa; Hunt, Richard C; Kratochvil, Christopher J.
Affiliation
  • Kraft CS; Colleen S. Kraft, MD, MSc, is Associate Professor, Department of Pathology and Laboratory Medicine, and Associate Professor, Division of Infectious Diseases, Emory University, Atlanta, GA.
  • Kortepeter MG; Mark G. Kortepeter, MD, MPH, is Professor of Epidemiology, Department of Epidemiology, University of Nebraska Medical Center, Omaha, NE.
  • Gordon B; Bruce Gordon, MD, is Professor, Division of Pediatric Hematology/Oncology, University of Nebraska Medical Center, Omaha, NE.
  • Sauer LM; Lauren M. Sauer, MS, is Assistant Professor, Director of Research, Johns Hopkins Biocontainment Unit, Department of Emergency Medicine, Johns Hopkins Medicine, Baltimore, MD.
  • Shenoy ES; Erica S. Shenoy, MD, PhD, is Assistant Professor of Medicine, Harvard Medical School, and Associate Chief, Infection Control Unit, Massachusetts General Hospital, Boston, MA.
  • Eiras DP; Daniel P. Eiras, MD, MPH, is Associate Hospital Epidemiologist, Infection Prevention and Control Department, NYU Langone Medical Center, New York, NY.
  • Larson L; LuAnn Larson, RN, BSN, is Director of Clinical Operations Nurse Manager, Clinical Research Biostatistics, University of Nebraska Medical Center, Omaha, NE.
  • Garland JA; Jennifer A. Garland, RN, PhD, is Special Pathogens Program Coordinator, Cedars-Sinai Medical Center, Los Angeles, CA.
  • Mehta AK; Aneesh K. Mehta, MD, is an Assistant Professor, Division of Infectious Diseases, Emory University, Atlanta, GA.
  • Barrett K; Kevin Barrett, RN, is a Nurse Specialist, NIH Clinical Center, the National Institute of Allergy and Infectious Diseases, Bethesda, MD.
  • Price CS; Connie S. Price, MD, is Professor of Medicine, University of Colorado School of Medicine, and Chief Medical Officer, Denver Health and Hospital, Denver, CO.
  • Croyle C; Caroline Croyle, MPH, is an Infection Prevention Specialist, Denver Health and Hospital, Denver, CO.
  • Noren B; Brooke Noren, RN, is Research Nurse Coordinator, University of Minnesota Medical Center, Minneapolis, MN.
  • Kline S; Susan Kline, MD, MPH, is Associate Professor of Medicine, Division of Infectious Diseases and International Medicine, University of Minnesota, Minneapolis, MN.
  • Arguinchona C; Christa Arguinchona is Assistant Nurse Manager, Providence Health and Services, Spokane, WA.
  • Arguinchona H; Henry Arguinchona, MD, is an infectious disease specialist, Providence Health and Services, Spokane, WA.
  • Grein JD; Jonathan D. Grein, MD, is Director, Hospital Epidemiology, Cedars-Sinai Medical Center, Los Angeles, CA.
  • Connally C; Chad Connally, RN, MSN, is Biocontainment and Emergency Management Program Manager, University of Texas Medical Branch, Galveston, TX.
  • McLellan S; Susan McLellan, MD, MPH, is Professor and Biocontainment Unit Director, University of Texas Medical Branch, Galveston, TX.
  • Risi GF; George F. Risi, MD, MSc, is Senior Medical Adviser, Tunnell Government Services, a contractor, BARDA, Office of the Assistant Secretary for Preparedness and Response, US Department of Health and Human Services, Washington, DC.
  • Uyeki TM; Timothy M. Uyeki, MD, MPH, is Chief Medical Officer, Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA.
  • Davey RT; Richard T. Davey, Jr., MD, is Chief, Clinical Research Section, the National Institute of Allergy and Infectious Diseases, Bethesda, MD.
  • Schweinle JE; Jo Ellen Schweinle, MD, is a Supervisory Health Scientist, BARDA, Office of the Assistant Secretary for Preparedness and Response, US Department of Health and Human Services, Washington, DC.
  • Schwedhelm MM; Michelle M. Schwedhelm, MSN, is Executive Director, Emergency Management & Biopreparedness, University of Nebraska Medical Center, Omaha, NE.
  • Harvey M; Melissa Cole Harvey, MSPH, is Director, Division of National Healthcare Preparedness Programs, Office of the Assistant Secretary for Preparedness and Response, US Department of Health and Human Services, Washington, DC.
  • Hunt RC; Richard C. Hunt, MD, MS, is Senior Medical Advisor, Division of National Healthcare Preparedness Programs, Office of the Assistant Secretary for Preparedness and Response, US Department of Health and Human Services, Washington, DC.
  • Kratochvil CJ; Christopher J. Kratochvil, MD, is Associate Vice Chancellor for Clinical Research, the University of Nebraska Medical Center, Omaha, NE.
Health Secur ; 17(1): 35-45, 2019 02.
Article in En | MEDLINE | ID: mdl-30779607
ABSTRACT
The 2013-2016 epidemic of Ebola virus disease (EVD) that originated in West Africa underscored many of the challenges to conducting clinical research during an ongoing infectious disease epidemic, both in the most affected countries of Guinea, Liberia, and Sierra Leone, as well as in the United States and Europe, where a total of 27 patients with EVD received care in biocontainment units. The Special Pathogens Research Network (SPRN) was established in the United States in November 2016 to provide an organizational structure to leverage the expertise of the 10 Regional Ebola and Other Special Pathogen Treatment Centers (RESPTCs); it was intended to develop and support infrastructure to improve readiness to conduct clinical research in the United States. The network enables the rapid activation and coordination of clinical research in the event of an epidemic and facilitates opportunities for multicenter research when the RESPTCs are actively caring for patients requiring a biocontainment unit. Here we provide an overview of opportunities identified in the clinical research infrastructure during the West Africa EVD epidemic and the SPRN activities to meet the ongoing challenges in the context of Ebola virus and other special pathogens.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Infection Control / Biomedical Research / Ebolavirus / Emergency Medical Services / Medical Countermeasures Limits: Humans Country/Region as subject: Africa / America do norte / Europa Language: En Journal: Health Secur Year: 2019 Document type: Article Affiliation country: Gabón
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Infection Control / Biomedical Research / Ebolavirus / Emergency Medical Services / Medical Countermeasures Limits: Humans Country/Region as subject: Africa / America do norte / Europa Language: En Journal: Health Secur Year: 2019 Document type: Article Affiliation country: Gabón