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A gastric resident drug delivery system for prolonged gram-level dosing of tuberculosis treatment.
Verma, Malvika; Vishwanath, Karan; Eweje, Feyisope; Roxhed, Niclas; Grant, Tyler; Castaneda, Macy; Steiger, Christoph; Mazdiyasni, Hormoz; Bensel, Taylor; Minahan, Daniel; Soares, Vance; Salama, John A F; Lopes, Aaron; Hess, Kaitlyn; Cleveland, Cody; Fulop, Daniel J; Hayward, Alison; Collins, Joy; Tamang, Siddartha M; Hua, Tiffany; Ikeanyi, Chinonyelum; Zeidman, Gal; Mule, Elizabeth; Boominathan, Sooraj; Popova, Ellena; Miller, Jonathan B; Bellinger, Andrew M; Collins, David; Leibowitz, Dalia; Batra, Shelly; Ahuja, Sandeep; Bajiya, Manju; Batra, Sonali; Sarin, Rohit; Agarwal, Upasna; Khaparde, Sunil D; Gupta, Neeraj K; Gupta, Deepak; Bhatnagar, Anuj K; Chopra, Kamal K; Sharma, Nandini; Khanna, Ashwani; Chowdhury, Jayeeta; Stoner, Robert; Slocum, Alexander H; Cima, Michael J; Furin, Jennifer; Langer, Robert; Traverso, Giovanni.
Affiliation
  • Verma M; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Vishwanath K; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Eweje F; Tata Center for Technology and Design, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Roxhed N; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Grant T; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Castaneda M; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Steiger C; Division of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Mazdiyasni H; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Bensel T; Department of Micro and Nanosystems, KTH Royal Institute of Technology, Stockholm 10044, Sweden.
  • Minahan D; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Soares V; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Salama JAF; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Lopes A; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Hess K; Division of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Cleveland C; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Fulop DJ; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Hayward A; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Collins J; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Tamang SM; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Hua T; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Ikeanyi C; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Zeidman G; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Mule E; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Boominathan S; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Popova E; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Miller JB; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Bellinger AM; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Collins D; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Leibowitz D; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Batra S; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Ahuja S; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Bajiya M; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Batra S; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Sarin R; Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Agarwal U; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Khaparde SD; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Gupta NK; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Gupta D; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Bhatnagar AK; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Chopra KK; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Sharma N; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Khanna A; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Chowdhury J; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Stoner R; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Slocum AH; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Cima MJ; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Furin J; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Langer R; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Traverso G; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Sci Transl Med ; 11(483)2019 03 13.
Article in En | MEDLINE | ID: mdl-30867322

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stomach / Tuberculosis / Drug Delivery Systems / Antitubercular Agents Limits: Animals / Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2019 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stomach / Tuberculosis / Drug Delivery Systems / Antitubercular Agents Limits: Animals / Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2019 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos