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TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance.
Lynch, Matthew R; Tran, Mei T; Ralto, Kenneth M; Zsengeller, Zsuzsanna K; Raman, Vinod; Bhasin, Swati S; Sun, Nuo; Chen, Xiuying; Brown, Daniel; Rovira, Ilsa I; Taguchi, Kensei; Brooks, Craig R; Stillman, Isaac E; Bhasin, Manoj K; Finkel, Toren; Parikh, Samir M.
Affiliation
  • Lynch MR; Division of Nephrology.
  • Tran MT; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
  • Ralto KM; Division of Nephrology.
  • Zsengeller ZK; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
  • Raman V; Division of Nephrology.
  • Bhasin SS; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
  • Sun N; Division of Nephrology.
  • Chen X; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
  • Brown D; Division of Nephrology.
  • Rovira II; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
  • Taguchi K; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
  • Brooks CR; Center for Molecular Medicine, National Heart, Lung and Blood Institute, NIH, Bethesda, Maryland, USA.
  • Stillman IE; Division of Nephrology.
  • Bhasin MK; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
  • Finkel T; Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
  • Parikh SM; Center for Molecular Medicine, National Heart, Lung and Blood Institute, NIH, Bethesda, Maryland, USA.
JCI Insight ; 52019 03 14.
Article in En | MEDLINE | ID: mdl-30870143

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organelle Biogenesis / Cisplatin / Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / Acute Kidney Injury / Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha / Kidney Tubules / Lysosomes / Mitochondria Type of study: Prognostic_studies Limits: Animals Language: En Journal: JCI Insight Year: 2019 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organelle Biogenesis / Cisplatin / Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / Acute Kidney Injury / Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha / Kidney Tubules / Lysosomes / Mitochondria Type of study: Prognostic_studies Limits: Animals Language: En Journal: JCI Insight Year: 2019 Document type: Article