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Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorable prognosis.
Lehman, Norman L; Usubalieva, Aisulu; Lin, Tong; Allen, Sariah J; Tran, Quynh T; Mobley, Bret C; McLendon, Roger E; Schniederjan, Matthew J; Georgescu, Maria-Magdalena; Couce, Marta; Dulai, Mohanpal S; Raisanen, Jack M; Al Abbadi, Mousa; Palmer, Cheryl A; Hattab, Eyas M; Orr, Brent A.
Affiliation
  • Lehman NL; Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, KY, 40292, USA. nllehman@yahoo.com.
  • Usubalieva A; Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
  • Lin T; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Allen SJ; Department of Pathology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.
  • Tran QT; Department of Pathology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.
  • Mobley BC; Department of Pathology, Vanderbilt University School of Medicine, Nashville, TN, 37232-2561, USA.
  • McLendon RE; Departments of Pathology, Duke University Medical Center, Durham, NC, 27710, USA.
  • Schniederjan MJ; Department of Pathology, Emory University, Atlanta, GA, 30322, USA.
  • Georgescu MM; Department of Pathology, Louisiana State University Health Shreveport, Shreveport, LA, 71103, USA.
  • Couce M; Department of Pathology, Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Dulai MS; Department of Pathology, Beaumont Hospital, Royal Oak, MI, 4807, USA.
  • Raisanen JM; Department of Pathology, The University of Texas Southwestern, Dallas, TX, 75390, USA.
  • Al Abbadi M; Department of Pathology, Microbiology and Forensic Medicine, University of Jordan, Amman, Jordan.
  • Palmer CA; Department of Pathology, University of Utah, Salt Lake City, UT, 84112, USA.
  • Hattab EM; Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, KY, 40292, USA.
  • Orr BA; Department of Pathology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA. brent.orr@stjude.org.
Acta Neuropathol Commun ; 7(1): 42, 2019 03 15.
Article in En | MEDLINE | ID: mdl-30876455
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Gene Rearrangement / Trans-Activators / Neoplasms, Neuroepithelial / Genomics / Tumor Suppressor Proteins / Proto-Oncogene Proteins B-raf Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male / Middle aged Language: En Journal: Acta Neuropathol Commun Year: 2019 Document type: Article Affiliation country: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Gene Rearrangement / Trans-Activators / Neoplasms, Neuroepithelial / Genomics / Tumor Suppressor Proteins / Proto-Oncogene Proteins B-raf Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male / Middle aged Language: En Journal: Acta Neuropathol Commun Year: 2019 Document type: Article Affiliation country: Estados Unidos