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Glycosylation-independent binding of monoclonal antibody toripalimab to FG loop of PD-1 for tumor immune checkpoint therapy.
Liu, Hongchuan; Guo, Lijing; Zhang, Jing; Zhou, Yuehua; Zhou, Jinwei; Yao, Jian; Wu, Hai; Yao, Sheng; Chen, Bo; Chai, Yan; Qi, Jianxun; Gao, George F; Tan, Shuguang; Feng, Hui; Yan, Jinghua.
Affiliation
  • Liu H; a Department of Antibody Discovery and Engineering , Shanghai Junshi Biosciences Co., Ltd , Shanghai , China.
  • Guo L; b Institute of Physical Science and Information Technology , Anhui University , Hefei , China.
  • Zhang J; c CAS Key Laboratory of Microbial Physiological and Metabolic Engineering , Institute of Microbiology, Chinese Academy of Sciences , Beijing China.
  • Zhou Y; a Department of Antibody Discovery and Engineering , Shanghai Junshi Biosciences Co., Ltd , Shanghai , China.
  • Zhou J; a Department of Antibody Discovery and Engineering , Shanghai Junshi Biosciences Co., Ltd , Shanghai , China.
  • Yao J; a Department of Antibody Discovery and Engineering , Shanghai Junshi Biosciences Co., Ltd , Shanghai , China.
  • Wu H; a Department of Antibody Discovery and Engineering , Shanghai Junshi Biosciences Co., Ltd , Shanghai , China.
  • Yao S; a Department of Antibody Discovery and Engineering , Shanghai Junshi Biosciences Co., Ltd , Shanghai , China.
  • Chen B; a Department of Antibody Discovery and Engineering , Shanghai Junshi Biosciences Co., Ltd , Shanghai , China.
  • Chai Y; a Department of Antibody Discovery and Engineering , Shanghai Junshi Biosciences Co., Ltd , Shanghai , China.
  • Qi J; d CAS Key Laboratory of Pathogenic Microbiology and Immunology , Institute of Microbiology, Chinese Academy of Sciences , Beijing , China.
  • Gao GF; d CAS Key Laboratory of Pathogenic Microbiology and Immunology , Institute of Microbiology, Chinese Academy of Sciences , Beijing , China.
  • Tan S; d CAS Key Laboratory of Pathogenic Microbiology and Immunology , Institute of Microbiology, Chinese Academy of Sciences , Beijing , China.
  • Feng H; b Institute of Physical Science and Information Technology , Anhui University , Hefei , China.
  • Yan J; d CAS Key Laboratory of Pathogenic Microbiology and Immunology , Institute of Microbiology, Chinese Academy of Sciences , Beijing , China.
MAbs ; 11(4): 681-690, 2019.
Article in En | MEDLINE | ID: mdl-30892132

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antibodies, Monoclonal, Humanized / Programmed Cell Death 1 Receptor / Immunotherapy / Melanoma / Antibodies, Monoclonal / Epitopes / Neoplasms, Experimental Limits: Animals / Humans Language: En Journal: MAbs Journal subject: ALERGIA E IMUNOLOGIA Year: 2019 Document type: Article Affiliation country: China Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antibodies, Monoclonal, Humanized / Programmed Cell Death 1 Receptor / Immunotherapy / Melanoma / Antibodies, Monoclonal / Epitopes / Neoplasms, Experimental Limits: Animals / Humans Language: En Journal: MAbs Journal subject: ALERGIA E IMUNOLOGIA Year: 2019 Document type: Article Affiliation country: China Country of publication: Estados Unidos