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Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
Bentley, Amy R; Sung, Yun J; Brown, Michael R; Winkler, Thomas W; Kraja, Aldi T; Ntalla, Ioanna; Schwander, Karen; Chasman, Daniel I; Lim, Elise; Deng, Xuan; Guo, Xiuqing; Liu, Jingmin; Lu, Yingchang; Cheng, Ching-Yu; Sim, Xueling; Vojinovic, Dina; Huffman, Jennifer E; Musani, Solomon K; Li, Changwei; Feitosa, Mary F; Richard, Melissa A; Noordam, Raymond; Baker, Jenna; Chen, Guanjie; Aschard, Hugues; Bartz, Traci M; Ding, Jingzhong; Dorajoo, Rajkumar; Manning, Alisa K; Rankinen, Tuomo; Smith, Albert V; Tajuddin, Salman M; Zhao, Wei; Graff, Mariaelisa; Alver, Maris; Boissel, Mathilde; Chai, Jin Fang; Chen, Xu; Divers, Jasmin; Evangelou, Evangelos; Gao, Chuan; Goel, Anuj; Hagemeijer, Yanick; Harris, Sarah E; Hartwig, Fernando P; He, Meian; Horimoto, Andrea R V R; Hsu, Fang-Chi; Hung, Yi-Jen; Jackson, Anne U.
Affiliation
  • Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA. amy.bentley@nih.gov.
  • Sung YJ; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.
  • Brown MR; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.
  • Kraja AT; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.
  • Ntalla I; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Schwander K; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.
  • Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Lim E; Harvard Medical School, Boston, MA, USA.
  • Deng X; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
  • Guo X; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
  • Liu J; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.
  • Lu Y; Women's Health Initiative Clinical Coordinating Center, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Cheng CY; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Sim X; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
  • Vojinovic D; Centre for Quantitative Medicine, Academic Medicine Research Institute, Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.
  • Huffman JE; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Musani SK; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
  • Li C; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.
  • Feitosa MF; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
  • Richard MA; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
  • Noordam R; Epidemiology and Biostatistics, University of Georgia at Athens College of Public Health, Athens, GA, USA.
  • Baker J; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.
  • Chen G; Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Aschard H; Internal Medicine, Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.
  • Bartz TM; Center for Research on Genomics and Global Health, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA.
  • Ding J; Center for Research on Genomics and Global Health, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA.
  • Dorajoo R; Centre de Bioinformatique, Biostatistique, et Biologie Intégrative (C3BI), Institut Pasteur, Paris, France.
  • Manning AK; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
  • Rankinen T; Cardiovascular Health Research Unit, Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Smith AV; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
  • Tajuddin SM; Center on Diabetes, Obesity, and Metabolism, Gerontology and Geriatric Medicine, Wake Forest University Health Sciences, Winston-Salem, NC, USA.
  • Zhao W; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.
  • Graff M; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA, USA.
  • Alver M; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Boissel M; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA.
  • Chai JF; Icelandic Heart Association, Kopavogur, Iceland.
  • Chen X; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
  • Divers J; Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, US National Institutes of Health, Baltimore, MD, USA.
  • Evangelou E; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
  • Gao C; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Goel A; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.
  • Hagemeijer Y; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France.
  • Harris SE; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
  • Hartwig FP; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • He M; Department of Biostatistics and Data Science, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA.
  • Horimoto ARVR; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, UK.
  • Hsu FC; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.
  • Hung YJ; Molecular Genetics and Genomics Program, Wake Forest School of Medicine, Winston-Salem, NC, USA.
  • Jackson AU; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Nat Genet ; 51(4): 636-648, 2019 04.
Article in En | MEDLINE | ID: mdl-30926973
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Smoking / Lipids Type of study: Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2019 Document type: Article Affiliation country: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Smoking / Lipids Type of study: Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2019 Document type: Article Affiliation country: Estados Unidos