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Repurposing of auranofin: Thioredoxin reductase remains a primary target of the drug.
Zhang, Xiaonan; Selvaraju, Karthik; Saei, Amir Ata; D'Arcy, Padraig; Zubarev, Roman A; Arnér, Elias Sj; Linder, Stig.
Affiliation
  • Zhang X; Department of Oncology-Pathology, Karolinska Institutet, SE-171 76, Stockholm, Sweden.
  • Selvaraju K; Department of Medical and Health Sciences, Linköping University, SE-581 83, Linköping, Sweden.
  • Saei AA; Department of Medical Biochemistry and Biophysics, Division of Physiological Chemistry I, Karolinska Institutet, SE-171 77, Stockholm, Sweden.
  • D'Arcy P; Department of Medical and Health Sciences, Linköping University, SE-581 83, Linköping, Sweden.
  • Zubarev RA; Department of Medical Biochemistry and Biophysics, Division of Physiological Chemistry I, Karolinska Institutet, SE-171 77, Stockholm, Sweden.
  • Arnér ES; Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institute, SE-171 77, Stockholm, Sweden.
  • Linder S; Department of Oncology-Pathology, Karolinska Institutet, SE-171 76, Stockholm, Sweden; Department of Medical and Health Sciences, Linköping University, SE-581 83, Linköping, Sweden. Electronic address: Stig.Linder@ki.se.
Biochimie ; 162: 46-54, 2019 Jul.
Article in En | MEDLINE | ID: mdl-30946948

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Auranofin / Selenoproteins / Thioredoxin Reductase 1 / Thioredoxin Reductase 2 / Drug Repositioning / Antineoplastic Agents Limits: Humans Language: En Journal: Biochimie Year: 2019 Document type: Article Affiliation country: Suecia Country of publication: Francia

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Auranofin / Selenoproteins / Thioredoxin Reductase 1 / Thioredoxin Reductase 2 / Drug Repositioning / Antineoplastic Agents Limits: Humans Language: En Journal: Biochimie Year: 2019 Document type: Article Affiliation country: Suecia Country of publication: Francia