Radiotherapy in the control of bleeding from primary and secondary lung tumours.
Br J Hosp Med (Lond)
; 80(4): 211-215, 2019 Apr 02.
Article
in En
| MEDLINE
| ID: mdl-30951418
ABSTRACT
This literature review clarifies the role of radiotherapy in the management of low-volume haemoptysis. Embase and Medline were interrogated, and PRISMA guidelines were then used to select relevant articles. Seventy-eight articles were considered relevant and manually reviewed. The evidence suggests that external beam radiotherapy is more effective than endobronchial brachytherapy at controlling low-volume haemoptysis. There is no evidence to recommend a combination of the two techniques. Different doses and fractionations appear equally effective, with a potential survival advantage of higher dose regimens for fitter patients. Palliative radiotherapy is effective at controlling low-volume haemoptysis. External beam radiotherapy is the first-line treatment, with endobronchial brachytherapy recommended following external beam radiotherapy failure. Choice of dose and fractionation should take into account the patient's performance status.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Carcinoma, Non-Small-Cell Lung
/
Small Cell Lung Carcinoma
/
Hemoptysis
/
Hemorrhage
/
Lung Neoplasms
Type of study:
Etiology_studies
/
Guideline
/
Systematic_reviews
Limits:
Humans
Language:
En
Journal:
Br J Hosp Med (Lond)
Journal subject:
HOSPITAIS
/
MEDICINA
Year:
2019
Document type:
Article