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Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9.
Hirano, Seiichi; Abudayyeh, Omar O; Gootenberg, Jonathan S; Horii, Takuro; Ishitani, Ryuichiro; Hatada, Izuho; Zhang, Feng; Nishimasu, Hiroshi; Nureki, Osamu.
Affiliation
  • Hirano S; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
  • Abudayyeh OO; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
  • Gootenberg JS; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Horii T; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
  • Ishitani R; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Hatada I; Laboratory of Genome Science, Biosignal Genome Resource Center, Institute for Molecular and Cellular Regulation, Gunma University, 3-39-15 Showa-machi, Maebashi, Gunma, 371-8512, Japan.
  • Zhang F; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
  • Nishimasu H; Laboratory of Genome Science, Biosignal Genome Resource Center, Institute for Molecular and Cellular Regulation, Gunma University, 3-39-15 Showa-machi, Maebashi, Gunma, 371-8512, Japan.
  • Nureki O; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
Nat Commun ; 10(1): 1968, 2019 04 29.
Article in En | MEDLINE | ID: mdl-31036811
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Restriction-Modification Enzymes / CRISPR-Associated Protein 9 Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Document type: Article Affiliation country: Japón Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Restriction-Modification Enzymes / CRISPR-Associated Protein 9 Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Document type: Article Affiliation country: Japón Country of publication: Reino Unido