Histone demethylase KDM5A is transactivated by the transcription factor C/EBPß and promotes preadipocyte differentiation by inhibiting Wnt/ß-catenin signaling.
J Biol Chem
; 294(24): 9642-9654, 2019 06 14.
Article
in En
| MEDLINE
| ID: mdl-31061100
Key words
3T3-L1 preadipocyte; C/EBPbeta; CCAAT/enhancer-binding protein (C/EBP); ChIP-on-chip; Wnt signaling; Wnt/beta-catenin pathway; adipogenesis; beta-catenin (B-catenin); chromatin immunoprecipitation (ChiP); epigenetics; fat cell; histone demethylase; lysine demethylase 5A (KDM5A); obesity; post-translational modification (PTM)
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cell Differentiation
/
Transcriptional Activation
/
Adipocytes
/
CCAAT-Enhancer-Binding Protein-beta
/
Wnt1 Protein
/
Beta Catenin
/
Retinoblastoma-Binding Protein 2
Type of study:
Prognostic_studies
Limits:
Animals
Language:
En
Journal:
J Biol Chem
Year:
2019
Document type:
Article
Affiliation country:
China
Country of publication:
Estados Unidos