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Loss of BRUCE reduces cellular energy level and induces autophagy by driving activation of the AMPK-ULK1 autophagic initiating axis.
Che, Lixiao; Yang, Xingyuan; Ge, Chunmin; El-Amouri, Salim S; Wang, Qi-En; Pan, Dao; Herzog, Thomas J; Du, Chunying.
Affiliation
  • Che L; Department of Cancer and Cell Biology, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America.
  • Yang X; Department of Cancer and Cell Biology, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America.
  • Ge C; Department of Cancer and Cell Biology, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America.
  • El-Amouri SS; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.
  • Wang QE; Department of Radiology, Ohio State University, Columbus, Ohio, United States of America.
  • Pan D; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.
  • Herzog TJ; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America.
  • Du C; Division of Obstetrics and Gynecology, University of Cincinnati, Cincinnati, Ohio, United States of America.
PLoS One ; 14(5): e0216553, 2019.
Article in En | MEDLINE | ID: mdl-31091257
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Autophagy / Osteosarcoma / Intracellular Signaling Peptides and Proteins / Energy Metabolism / Inhibitor of Apoptosis Proteins / AMP-Activated Protein Kinases / Autophagy-Related Protein-1 Homolog Limits: Female / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2019 Document type: Article Affiliation country: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Autophagy / Osteosarcoma / Intracellular Signaling Peptides and Proteins / Energy Metabolism / Inhibitor of Apoptosis Proteins / AMP-Activated Protein Kinases / Autophagy-Related Protein-1 Homolog Limits: Female / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2019 Document type: Article Affiliation country: Estados Unidos