[Multi-Faceted Symptoms with Joint Pain, Exanthema and Eye Involvement]. / Facettenreiche Symptomatik mit Gelenkschmerzen, Exanthem und Augenbeteiligung.
Dtsch Med Wochenschr
; 144(11): 759-763, 2019 06.
Article
in De
| MEDLINE
| ID: mdl-31163477
ABSTRACT
HISTORY AND ADMISSION FINDINGS:
In this case series, we describe 4 patients who presented to a rheumatologic clinic with very different complains however were ultimately diagnosed with the same underlying disease. The wide spectrum of symptoms included generalized maculopapular exanthema, arthralgia, myalgia and vision problems. One patient received anti-TNF therapy for ankylosing spondylitis and recurrent uveitis. On exam, joint swelling and skin changes were found. INVESTIGATION All patients were found to have an elevated Treponema pallidum antibody titer and a positive of the rapid plasma reagin test. DIAGNOSIS Patients were diagnosed with syphilis. TREATMENT AND COURSE The first three patients received an intramuscular injection of 2.4 million benzabine penicillin G. The fourth patient was treated with penicillin 6 million IV 4 times a day for more than 14 days, due to immunosuppressionCONCLUSION:
In the presence of non-specific and often rather diffuse symptoms, with which patients in rheumatology often present, a non-primary rheumatological, e.âg. infectious genesis, also needs to be considered. Due to the increasing incidence of syphilis in Germany in recent years special attention needs to be paid to this disease in rheumatological care.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Treponema pallidum
/
Syphilis
/
Eye Infections, Bacterial
/
Arthralgia
/
Exanthema
Type of study:
Diagnostic_studies
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
De
Journal:
Dtsch Med Wochenschr
Year:
2019
Document type:
Article