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The plant product quinic acid activates Ca2+ -dependent mitochondrial function and promotes insulin secretion from pancreatic beta cells.
Heikkilä, Eija; Hermant, Aurelie; Thevenet, Jonathan; Bermont, Flavien; Kulkarni, Sameer S; Ratajczak, Joanna; Santo-Domingo, Jaime; Dioum, El Hadji; Canto, Carles; Barron, Denis; Wiederkehr, Andreas; De Marchi, Umberto.
Affiliation
  • Heikkilä E; Nestlé Research, EPFL Innovation Park, Lausanne, Switzerland.
  • Hermant A; Nestlé Research, EPFL Innovation Park, Lausanne, Switzerland.
  • Thevenet J; Nestlé Research, EPFL Innovation Park, Lausanne, Switzerland.
  • Bermont F; Nestlé Research, EPFL Innovation Park, Lausanne, Switzerland.
  • Kulkarni SS; Nestlé Research, EPFL Innovation Park, Lausanne, Switzerland.
  • Ratajczak J; Nestlé Research, EPFL Innovation Park, Lausanne, Switzerland.
  • Santo-Domingo J; Nestlé Research, EPFL Innovation Park, Lausanne, Switzerland.
  • Dioum EH; Nestlé Research, EPFL Innovation Park, Lausanne, Switzerland.
  • Canto C; Nestlé Research, EPFL Innovation Park, Lausanne, Switzerland.
  • Barron D; Nestlé Research, EPFL Innovation Park, Lausanne, Switzerland.
  • Wiederkehr A; Nestlé Research, EPFL Innovation Park, Lausanne, Switzerland.
  • De Marchi U; Nestlé Research, EPFL Innovation Park, Lausanne, Switzerland.
Br J Pharmacol ; 176(17): 3250-3263, 2019 09.
Article in En | MEDLINE | ID: mdl-31166006
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinic Acid / Biological Products / Calcium / Insulin-Secreting Cells / Insulin Secretion / Mitochondria Type of study: Prognostic_studies Limits: Animals Language: En Journal: Br J Pharmacol Year: 2019 Document type: Article Affiliation country: Suiza Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinic Acid / Biological Products / Calcium / Insulin-Secreting Cells / Insulin Secretion / Mitochondria Type of study: Prognostic_studies Limits: Animals Language: En Journal: Br J Pharmacol Year: 2019 Document type: Article Affiliation country: Suiza Country of publication: Reino Unido