Therapeutic benefits of maintaining mitochondrial integrity and calcium homeostasis by forced expression of Hsp27 in chemotherapy-induced peripheral neuropathy.

Chine, Virendra Bhagawan; Au, Ngan Pan Bennett; Ma, Chi Him Eddie

Chine, Virendra Bhagawan; Au, Ngan Pan Bennett; Ma, Chi Him Eddie.

Affiliation

Chine VB; Department of Biomedical Sciences, City University of Hong Kong, Tat Chee Avenue, Hong Kong.
Au NPB; Department of Biomedical Sciences, City University of Hong Kong, Tat Chee Avenue, Hong Kong.
Ma CHE; Department of Biomedical Sciences, City University of Hong Kong, Tat Chee Avenue, Hong Kong; Centre for Biosystems, Neuroscience, and Nanotechnology, City University of Hong Kong, Tat Chee Avenue, Hong Kong; State Key Laboratory in Marine Pollution, City University of Hong Kong, Tat Chee Avenue, Hong Kong. Electronic address: eddiema@cityu.edu.hk.

Neurobiol Dis ; 130: 104492, 2019 10.

Article in En | MEDLINE | ID: mdl-31176721

Subject(s)
Key words

Axon degeneration; Chemotherapy-induced peripheral neuropathy; Demyelination; Heat shock protein 27; Intracellular calcium; Mechanical and cold allodynia; Vincristine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Calcium / Peripheral Nervous System Diseases / Neurotoxicity Syndromes / HSP27 Heat-Shock Proteins / Mitochondria Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2019 Document type: Article Affiliation country: Hong Kong

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