Ganglioside GQ1b ameliorates cognitive impairments in an Alzheimer's disease mouse model, and causes reduction of amyloid precursor protein.

Shin, Min-Kyoo; Choi, Min-Suk; Chae, Hyang-Ji; Kim, Ji-Won; Kim, Hong-Gi; Kim, Kil-Lyong

Shin, Min-Kyoo; Choi, Min-Suk; Chae, Hyang-Ji; Kim, Ji-Won; Kim, Hong-Gi; Kim, Kil-Lyong.

Affiliation

Shin MK; Department of Biological Sciences, Sungkyunkwan University, 2066, Seobu-ro, Jangan-gu, Suwon-si, Gyeonggi-do, 16419, Republic of Korea.
Choi MS; Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, 141, Gajeong-ro, Yuseong-gu, Daejeon, 34114, Republic of Korea.
Chae HJ; Department of Biological Sciences, Sungkyunkwan University, 2066, Seobu-ro, Jangan-gu, Suwon-si, Gyeonggi-do, 16419, Republic of Korea.
Kim JW; Department of Biological Sciences, Sungkyunkwan University, 2066, Seobu-ro, Jangan-gu, Suwon-si, Gyeonggi-do, 16419, Republic of Korea.
Kim HG; Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, 141, Gajeong-ro, Yuseong-gu, Daejeon, 34114, Republic of Korea. tenork@krict.re.kr.
Kim KL; Department of Biological Sciences, Sungkyunkwan University, 2066, Seobu-ro, Jangan-gu, Suwon-si, Gyeonggi-do, 16419, Republic of Korea. kimkl@skku.edu.

Sci Rep ; 9(1): 8512, 2019 06 11.

Article in En | MEDLINE | ID: mdl-31186474

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Amyloid beta-Protein Precursor / Alzheimer Disease / Cognitive Dysfunction / Gangliosides Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Sci Rep Year: 2019 Document type: Article Country of publication: Reino Unido

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