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An ATR and CHK1 kinase signaling mechanism that limits origin firing during unperturbed DNA replication.
Moiseeva, Tatiana N; Yin, Yandong; Calderon, Michael J; Qian, Chenao; Schamus-Haynes, Sandra; Sugitani, Norie; Osmanbeyoglu, Hatice U; Rothenberg, Eli; Watkins, Simon C; Bakkenist, Christopher J.
Affiliation
  • Moiseeva TN; Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Yin Y; Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016.
  • Calderon MJ; Department of Cell Biology, Center for Biologic Imaging, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261.
  • Qian C; Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA 15260.
  • Schamus-Haynes S; Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Sugitani N; Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Osmanbeyoglu HU; Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15206.
  • Rothenberg E; Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016.
  • Watkins SC; Department of Cell Biology, Center for Biologic Imaging, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261.
  • Bakkenist CJ; Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213; bakkenistcj@upmc.edu.
Proc Natl Acad Sci U S A ; 116(27): 13374-13383, 2019 07 02.
Article in En | MEDLINE | ID: mdl-31209037
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / DNA Replication / Ataxia Telangiectasia Mutated Proteins / Checkpoint Kinase 1 Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2019 Document type: Article Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / DNA Replication / Ataxia Telangiectasia Mutated Proteins / Checkpoint Kinase 1 Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2019 Document type: Article Country of publication: Estados Unidos