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Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development.
Gui, Xun; Deng, Mi; Song, Hao; Chen, Yuanzhi; Xie, Jingjing; Li, Zunling; He, Licai; Huang, Fangfang; Xu, Yixiang; Anami, Yasuaki; Yu, Hai; Yu, Chenyi; Li, Leike; Yuan, Zihao; Xu, Xiaoying; Wang, Qihui; Chai, Yan; Huang, Tao; Shi, Yi; Tsuchikama, Kyoji; Liao, X Charlene; Xia, Ningshao; Gao, George F; Zhang, Ningyan; Zhang, Cheng Cheng; An, Zhiqiang.
Affiliation
  • Gui X; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas.
  • Deng M; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Song H; Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.
  • Chen Y; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas.
  • Xie J; School of Public Health, Xiamen University, Xiamen, Fujian, China.
  • Li Z; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas.
  • He L; Taishan Immunology Program, Basic Medicine School, Binzhou Medical University, Yantai, China.
  • Huang F; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Xu Y; Taishan Immunology Program, Basic Medicine School, Binzhou Medical University, Yantai, China.
  • Anami Y; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Yu H; Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medical and Life Science, Wenzhou Medical University, Wenzhou, China.
  • Yu C; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Li L; Department of Hematology, Zhongshan Hospital, Xiamen University, Xiamen, China.
  • Yuan Z; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas.
  • Xu X; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas.
  • Wang Q; School of Public Health, Xiamen University, Xiamen, Fujian, China.
  • Chai Y; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas.
  • Huang T; School of Xiangya Medicine, Central South University, Changsha, Hunan, China.
  • Shi Y; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas.
  • Tsuchikama K; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas.
  • Liao XC; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
  • Xia N; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas.
  • Gao GF; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
  • Zhang N; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
  • Zhang CC; Immune-Onc Therapeutics, Inc., Palo Alto, California.
  • An Z; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Cancer Immunol Res ; 7(8): 1244-1257, 2019 08.
Article in En | MEDLINE | ID: mdl-31213474
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins E / Membrane Glycoproteins / Receptors, Immunologic / T-Lymphocytes / Leukemia, Myeloid, Acute / Cell Transformation, Neoplastic / Antineoplastic Agents, Immunological Limits: Animals / Humans Language: En Journal: Cancer Immunol Res Year: 2019 Document type: Article
Fulltext
Add to My VHL
Print
XML
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins E / Membrane Glycoproteins / Receptors, Immunologic / T-Lymphocytes / Leukemia, Myeloid, Acute / Cell Transformation, Neoplastic / Antineoplastic Agents, Immunological Limits: Animals / Humans Language: En Journal: Cancer Immunol Res Year: 2019 Document type: Article