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Pexidartinib versus placebo for advanced tenosynovial giant cell tumour (ENLIVEN): a randomised phase 3 trial.
Tap, William D; Gelderblom, Hans; Palmerini, Emanuela; Desai, Jayesh; Bauer, Sebastian; Blay, Jean-Yves; Alcindor, Thierry; Ganjoo, Kristen; Martín-Broto, Javier; Ryan, Christopher W; Thomas, David M; Peterfy, Charles; Healey, John H; van de Sande, Michiel; Gelhorn, Heather L; Shuster, Dale E; Wang, Qiang; Yver, Antoine; Hsu, Henry H; Lin, Paul S; Tong-Starksen, Sandra; Stacchiotti, Silvia; Wagner, Andrew J.
Affiliation
  • Tap WD; Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY, USA. Electronic address: tapw@mskcc.org.
  • Gelderblom H; Leiden University Medical Center, Leiden, Netherlands.
  • Palmerini E; IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
  • Desai J; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Bauer S; Sarcoma Center, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
  • Blay JY; Centre Léon Bérard and Université Claude Bernard, Lyon, France.
  • Alcindor T; McGill University, Montreal, QC, Canada.
  • Ganjoo K; Stanford University Medical Center, Stanford, CA, USA.
  • Martín-Broto J; Institute of Biomedicine of Sevilla, (IBIS, HUVR, CSIC, Universidad de Sevilla), Sevilla, Spain.
  • Ryan CW; Oregon Health and Science University, Portland, OR, USA.
  • Thomas DM; Chris O'Brien Lifehouse, Camperdown, NSW, Australia.
  • Peterfy C; Spire Sciences, Boca Raton, FL, USA.
  • Healey JH; Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY, USA.
  • van de Sande M; Leiden University Medical Center, Leiden, Netherlands.
  • Gelhorn HL; Evidera, Bethesda, MD, USA.
  • Shuster DE; Daiichi Sankyo, Inc, Basking Ridge, NJ, USA.
  • Wang Q; Daiichi Sankyo, Inc, Basking Ridge, NJ, USA.
  • Yver A; Daiichi Sankyo, Inc, Basking Ridge, NJ, USA.
  • Hsu HH; Plexxikon, Berkeley, CA, USA.
  • Lin PS; Plexxikon, Berkeley, CA, USA.
  • Tong-Starksen S; Plexxikon, Berkeley, CA, USA.
  • Stacchiotti S; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Wagner AJ; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
Lancet ; 394(10197): 478-487, 2019 08 10.
Article in En | MEDLINE | ID: mdl-31229240
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase Inhibitors / Giant Cell Tumor of Tendon Sheath / Antineoplastic Agents Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Lancet Year: 2019 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase Inhibitors / Giant Cell Tumor of Tendon Sheath / Antineoplastic Agents Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Lancet Year: 2019 Document type: Article