[Tumors with predominantly adipocytic morphology]. / Tumoren mit prädominant adipozytärer Morphologie.
Pathologe
; 40(4): 339-352, 2019 Jul.
Article
in De
| MEDLINE
| ID: mdl-31240452
ABSTRACT
More than 20% of soft-tissue tumors belong to the group of adipocytic neoplasms. Difficulties may occur in the differential diagnosis of lipomas versus atypical lipomatous tumors/well-differentiated liposarcomas, in the distinction of dedifferentiated liposarcomas from other soft-tissue sarcoma entities and in the detailed subtyping of liposarcomas. Especially in biopsies, the correct diagnosis and grading may be hampered due to limited tissue. Because of the ever-increasing molecular-pathological knowledge of soft-tissue tumors and the rising distribution of molecular diagnostic assays in institutes of pathology, differential diagnosis has been facilitated, as more than 90% of adipocytic tumors carry more or less specific genomic alterations. In the following, the most important subtypes of adipocytic tumors are described morphologically and genomically.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sarcoma
/
Soft Tissue Neoplasms
/
Neoplasms, Adipose Tissue
/
Lipoma
/
Liposarcoma
Type of study:
Diagnostic_studies
Limits:
Humans
Language:
De
Journal:
Pathologe
Year:
2019
Document type:
Article