[Outcomes of patients treated with drug-coated balloons for de novo large coronary vessels].
Zhonghua Xin Xue Guan Bing Za Zhi
; 47(6): 452-456, 2019 Jun 24.
Article
in Zh
| MEDLINE
| ID: mdl-31262129
ABSTRACT
Objective:
To evaluate the efficacy and safety of drug-coated balloons (DCB) for de novo large coronary vessels.Methods:
One hundred and two patients were retrospectively enrolled in this study, there were 104 lesions with the reference lumen diameter of target vessel more than 2.8 mm and patients were treated with DCB in de novo lesions during May 2015 and July 2017 in our center. Coronary artery angiography and quantitative coronary angiography were performed in 82 (80.4%) patients at follow up period ((8.1±1.7) months post procedure). The endpoints were late lumen loss (LLL) at follow up,and major adverse cardiac events (MACE) including cardiac death, myocardial infarction (MI), target lesion revascularization (TLR) and stent or target lesion thrombosis at 12 months post procedure.Results:
Ninety-eight lesions were treated with DCB only, 6 (5.9%) bailout drug-eluting stent (DES) were used because of severe coronary dissection, 2 patients (2.0%) received revascularization driven by acute ischemic events during hospitalization. Cutting balloons and NSE balloons were used in 65.4% (68/104) and 26.0% (27/104) lesions. The lesion length was (12.57±3.58) mm and the DCB length was (19.87±4.55) mm. The late lumen loss was (0.01±0.52) mm during angiographic follow up. The TLR rate and overall MACE rate was 3.9% (4/102) and 3.9% (4/102) and there was no death,MI and target lesion thrombosis at 12 months follow up.Conclusion:
DCB treatment for de novo large coronary vessels is effective and safe.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Coronary Artery Disease
/
Coronary Restenosis
/
Drug-Eluting Stents
Type of study:
Observational_studies
Limits:
Humans
Language:
Zh
Journal:
Zhonghua Xin Xue Guan Bing Za Zhi
Year:
2019
Document type:
Article
Affiliation country:
China