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Functional systemic CD4 immunity is required for clinical responses to PD-L1/PD-1 blockade therapy.
Zuazo, Miren; Arasanz, Hugo; Fernández-Hinojal, Gonzalo; García-Granda, Maria Jesus; Gato, María; Bocanegra, Ana; Martínez, Maite; Hernández, Berta; Teijeira, Lucía; Morilla, Idoia; Lecumberri, Maria Jose; Fernández de Lascoiti, Angela; Vera, Ruth; Kochan, Grazyna; Escors, David.
Affiliation
  • Zuazo M; Immunomodulation Group, Biomedical Research Center of Navarre-Navarrabiomed, Fundación Miguel Servet, IdISNA, Pamplona, Spain.
  • Arasanz H; Immunomodulation Group, Biomedical Research Center of Navarre-Navarrabiomed, Fundación Miguel Servet, IdISNA, Pamplona, Spain.
  • Fernández-Hinojal G; Department of Oncology, Hospital Complex of Navarre, IdISNA, Pamplona, Spain.
  • García-Granda MJ; Immunomodulation Group, Biomedical Research Center of Navarre-Navarrabiomed, Fundación Miguel Servet, IdISNA, Pamplona, Spain.
  • Gato M; Immunomodulation Group, Biomedical Research Center of Navarre-Navarrabiomed, Fundación Miguel Servet, IdISNA, Pamplona, Spain.
  • Bocanegra A; Immunomodulation Group, Biomedical Research Center of Navarre-Navarrabiomed, Fundación Miguel Servet, IdISNA, Pamplona, Spain.
  • Martínez M; Department of Oncology, Hospital Complex of Navarre, IdISNA, Pamplona, Spain.
  • Hernández B; Department of Oncology, Hospital Complex of Navarre, IdISNA, Pamplona, Spain.
  • Teijeira L; Department of Oncology, Hospital Complex of Navarre, IdISNA, Pamplona, Spain.
  • Morilla I; Department of Oncology, Hospital Complex of Navarre, IdISNA, Pamplona, Spain.
  • Lecumberri MJ; Department of Oncology, Hospital Complex of Navarre, IdISNA, Pamplona, Spain.
  • Fernández de Lascoiti A; Department of Oncology, Hospital Complex of Navarre, IdISNA, Pamplona, Spain.
  • Vera R; Department of Oncology, Hospital Complex of Navarre, IdISNA, Pamplona, Spain.
  • Kochan G; Immunomodulation Group, Biomedical Research Center of Navarre-Navarrabiomed, Fundación Miguel Servet, IdISNA, Pamplona, Spain.
  • Escors D; Immunomodulation Group, Biomedical Research Center of Navarre-Navarrabiomed, Fundación Miguel Servet, IdISNA, Pamplona, Spain.
EMBO Mol Med ; 11(7): e10293, 2019 07.
Article in En | MEDLINE | ID: mdl-31273938
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / B7-H1 Antigen / Programmed Cell Death 1 Receptor / Immunity, Cellular / Immunologic Memory / Immunotherapy / Lung Neoplasms / Neoplasm Proteins Type of study: Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: EMBO Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2019 Document type: Article Affiliation country: España Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / B7-H1 Antigen / Programmed Cell Death 1 Receptor / Immunity, Cellular / Immunologic Memory / Immunotherapy / Lung Neoplasms / Neoplasm Proteins Type of study: Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: EMBO Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2019 Document type: Article Affiliation country: España Country of publication: Reino Unido