Application of a novel material in the inguinal region using a totally percutaneous approach in an animal model: a new potential technique?
Hernia
; 23(6): 1175-1185, 2019 Dec.
Article
in En
| MEDLINE
| ID: mdl-31312941
ABSTRACT
PURPOSE:
To evaluate the feasibility and safety of a new percutaneous image-guided surgery technique to simulate a hernia repair using hydrogel. MATERIALS ANDMETHODS:
A comparative prospective study was conducted in animals, with survival. Five pigs without any hernias were used. A hydrogel was injected at a site corresponding to the preperitoneal inguinal region. This procedure was performed bilaterally. An image-guided needle (ultrasound and computed tomography) was used, through which the material was injected. After survival, the local and systemic inflammatory reaction generated by the new material, was studied.RESULTS:
All animals survived the procedure. No hemorrhagic or infectious complications were reported. The solidification of the material occurred as expected. In eight out of ten cases, the material was found in the planned site. No systemic inflammatory reaction secondary to the administration of hydrogel was reported. The adhesion of the material to surrounding tissues was satisfactory.CONCLUSION:
The introduction of a liquid material which solidifies after injection in a short time (hydrogel) using a needle is feasible. The combined CT-scan and US image guidance allows for the percutaneous placement of the needle in the required location. The introduced hydrogel remains in this space, corresponding to the inguinal region, without moving. The placed hydrogel compresses the posterior wall composed of the transversalis fascia, supporting the potential use of hydrogel for hernia defects.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Biocompatible Materials
/
Hydrogels
/
Surgery, Computer-Assisted
/
Herniorrhaphy
/
Hernia, Inguinal
Type of study:
Diagnostic_studies
/
Observational_studies
Limits:
Animals
Language:
En
Journal:
Hernia
Journal subject:
GASTROENTEROLOGIA
Year:
2019
Document type:
Article
Affiliation country:
Francia
Publication country:
FR
/
FRANCE
/
FRANCIA
/
FRANÇA