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Indomethacin reduces rates of aortic dissection and rupture of the abdominal aorta by inhibiting monocyte/macrophage accumulation in a murine model.
Tomida, Shota; Aizawa, Kenichi; Nishida, Norifumi; Aoki, Hiroki; Imai, Yasushi; Nagai, Ryozo; Suzuki, Toru.
Affiliation
  • Tomida S; Department of Clinical Pharmacology, Jichi Medical University, Tochigi, Japan.
  • Aizawa K; Department of Clinical Pharmacology, Jichi Medical University, Tochigi, Japan.
  • Nishida N; Division of Cardiovascular Medicine, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
  • Aoki H; Cardiovascular Research Institute, Kurume University, Kurume, Japan.
  • Imai Y; Department of Clinical Pharmacology, Jichi Medical University, Tochigi, Japan.
  • Nagai R; Jichi Medical University, Tochigi, Japan.
  • Suzuki T; Department of Cardiovascular Sciences, University of Leicester, Cardiovascular Research Centre, Leicester, UK. ts263@le.ac.uk.
Sci Rep ; 9(1): 10751, 2019 07 24.
Article in En | MEDLINE | ID: mdl-31341173
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aortic Rupture / Monocytes / Anti-Inflammatory Agents, Non-Steroidal / Indomethacin / Aortic Aneurysm, Abdominal / Aortic Dissection / Macrophages Limits: Animals Language: En Journal: Sci Rep Year: 2019 Document type: Article Affiliation country: Japón Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aortic Rupture / Monocytes / Anti-Inflammatory Agents, Non-Steroidal / Indomethacin / Aortic Aneurysm, Abdominal / Aortic Dissection / Macrophages Limits: Animals Language: En Journal: Sci Rep Year: 2019 Document type: Article Affiliation country: Japón Country of publication: Reino Unido