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C-terminal proteolysis of the collagen VI α3 chain by BMP-1 and proprotein convertase(s) releases endotrophin in fragments of different sizes.
Heumüller, Stefanie Elisabeth; Talantikite, Maya; Napoli, Manon; Armengaud, Jean; Mörgelin, Matthias; Hartmann, Ursula; Sengle, Gerhard; Paulsson, Mats; Moali, Catherine; Wagener, Raimund.
Affiliation
  • Heumüller SE; Center for Biochemistry, Faculty of Medicine, University of Cologne, 50931 Cologne, Germany.
  • Talantikite M; Tissue Biology and Therapeutic Engineering Laboratory, UMR5305 CNRS/University of Lyon, 69367 Lyon, France.
  • Napoli M; Tissue Biology and Therapeutic Engineering Laboratory, UMR5305 CNRS/University of Lyon, 69367 Lyon, France.
  • Armengaud J; Commissariat à l'Energie Atomique (CEA)-Marcoule, DRF/JOLIOT/DMTS/SPI/Li2D, Innovative Technologies for Detection and Diagnostics Laboratory, 30200 Bagnols-sur-Cèze, France.
  • Mörgelin M; Colzyx AB, Medicon Village, SE-223 81 Lund, Sweden.
  • Hartmann U; Center for Biochemistry, Faculty of Medicine, University of Cologne, 50931 Cologne, Germany.
  • Sengle G; Center for Biochemistry, Faculty of Medicine, University of Cologne, 50931 Cologne, Germany.
  • Paulsson M; Cologne Center for Musculoskeletal Biomechanics (CCMB), 50931 Cologne, Germany.
  • Moali C; Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931 Cologne, Germany.
  • Wagener R; Department of Pediatrics and Adolescent Medicine, Experimental Neonatology, Faculty of Medicine and University Hospital Cologne, 50931 Cologne, Germany.
J Biol Chem ; 294(37): 13769-13780, 2019 09 13.
Article in En | MEDLINE | ID: mdl-31346034
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Collagen Type VI / Proprotein Convertases / Bone Morphogenetic Protein 1 Limits: Humans Language: En Journal: J Biol Chem Year: 2019 Document type: Article Affiliation country: Alemania
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Collagen Type VI / Proprotein Convertases / Bone Morphogenetic Protein 1 Limits: Humans Language: En Journal: J Biol Chem Year: 2019 Document type: Article Affiliation country: Alemania