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A genome-wide positioning systems network algorithm for in silico drug repurposing.
Cheng, Feixiong; Lu, Weiqiang; Liu, Chuang; Fang, Jiansong; Hou, Yuan; Handy, Diane E; Wang, Ruisheng; Zhao, Yuzheng; Yang, Yi; Huang, Jin; Hill, David E; Vidal, Marc; Eng, Charis; Loscalzo, Joseph.
Affiliation
  • Cheng F; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.
  • Lu W; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, 44195, USA.
  • Liu C; Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
  • Fang J; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
  • Hou Y; Alibaba Research Center for Complexity Sciences, Hangzhou Normal University, 311121, Hangzhou, China.
  • Handy DE; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.
  • Wang R; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.
  • Zhao Y; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
  • Yang Y; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
  • Huang J; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 200237, Shanghai, China.
  • Hill DE; Synthetic Biology and Biotechnology Laboratory, State Key Laboratory of Bioreactor Engineering, Shanghai Collaborative Innovation Center for Biomanufacturing Technology, 200237, Shanghai, China.
  • Vidal M; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 200237, Shanghai, China.
  • Eng C; Synthetic Biology and Biotechnology Laboratory, State Key Laboratory of Bioreactor Engineering, Shanghai Collaborative Innovation Center for Biomanufacturing Technology, 200237, Shanghai, China.
  • Loscalzo J; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 200237, Shanghai, China.
Nat Commun ; 10(1): 3476, 2019 08 02.
Article in En | MEDLINE | ID: mdl-31375661
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Algorithms / Systems Biology / Drug Repositioning Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Algorithms / Systems Biology / Drug Repositioning Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido