Location of Retinal Nerve Fiber Layer Defects in Open-angle Glaucoma and Associated Factors.
Korean J Ophthalmol
; 33(4): 379-385, 2019 Aug.
Article
in En
| MEDLINE
| ID: mdl-31389215
ABSTRACT
PURPOSE:
To investigate the location of retinal nerve fiber layer defects (RNFLDs) in open-angle glaucoma and the differences in systemic and ocular factors between superotemporal and inferotemporal RNFLDs.METHODS:
We performed a retrospective review of the 2008 to 2012 data from the Korea National Health and Nutrition Examination Survey. Subjects aged ≥19 years with an evaluable fundus photograph of at least one eye were enrolled, and open-angle glaucoma was diagnosed according to modified International Society of Geographical and Epidemiological Ophthalmology criteria. In subjects with open-angle glaucoma, locations of RNFLDs were evaluated, and systemic and ocular factors were compared between the bilateral superotemporal RNFLD group and bilateral inferotemporal RNFLD group.RESULTS:
A total of 534 subjects had open-angle glaucoma with RNFLDs. The unilateral inferotemporal region (25.8%) was the most common location for RNFLDs, followed by the unilateral superotemporal region (24.4%). Multivariate analysis revealed that hypertension was more significantly associated (p = 0.048) with the bilateral superotemporal RNFLD group than with the bilateral inferotemporal RNFLD group.CONCLUSIONS:
Superotemporal RNFLDs are more related to hypertension than are inferotemporal RNFLDs.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Retinal Ganglion Cells
/
Visual Fields
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Glaucoma, Open-Angle
/
Population Surveillance
/
Intraocular Pressure
/
Nerve Fibers
Type of study:
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Limits:
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Korean J Ophthalmol
Journal subject:
OFTALMOLOGIA
Year:
2019
Document type:
Article