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Population Pharmacokinetics of Apalutamide and its Active Metabolite N-Desmethyl-Apalutamide in Healthy and Castration-Resistant Prostate Cancer Subjects.
Pérez-Ruixo, Carlos; Pérez-Blanco, Jonás Samuel; Chien, Caly; Yu, Margaret; Ouellet, Daniele; Pérez-Ruixo, Juan-José; Ackaert, Oliver.
Affiliation
  • Pérez-Ruixo C; Janssen Research & Development, Antwerp, Belgium.
  • Pérez-Blanco JS; Janssen Research & Development, Antwerp, Belgium.
  • Chien C; Janssen Research & Development, Spring House, PA, USA.
  • Yu M; Janssen Research & Development, Los Angeles, CA, USA.
  • Ouellet D; Janssen Research & Development, Spring House, PA, USA.
  • Pérez-Ruixo JJ; Janssen Research & Development, Antwerp, Belgium.
  • Ackaert O; Janssen Research & Development, Antwerp, Belgium. oackaert@its.jnj.com.
Clin Pharmacokinet ; 59(2): 229-244, 2020 02.
Article in En | MEDLINE | ID: mdl-31432469
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiohydantoins / Albumins / Androgen Receptor Antagonists / Prostatic Neoplasms, Castration-Resistant Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Aspects: Patient_preference Limits: Adult / Aged / Aged80 / Humans / Male / Middle aged Language: En Journal: Clin Pharmacokinet Year: 2020 Document type: Article Affiliation country: Bélgica Country of publication: Suiza
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiohydantoins / Albumins / Androgen Receptor Antagonists / Prostatic Neoplasms, Castration-Resistant Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Aspects: Patient_preference Limits: Adult / Aged / Aged80 / Humans / Male / Middle aged Language: En Journal: Clin Pharmacokinet Year: 2020 Document type: Article Affiliation country: Bélgica Country of publication: Suiza