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Mitochondrial oxidative stress plays a critical role in the cardiotoxicity of sunitinib: Running title: Sunitinib and oxidative stress in hearts.
Bouitbir, Jamal; Alshaikhali, Abdallah; Panajatovic, Miljenko V; Abegg, Vanessa F; Paech, Franziska; Krähenbühl, Stephan.
Affiliation
  • Bouitbir J; Division of Clinical Pharmacology & Toxicology, University Hospital, Basel, Switzerland; Department of Biomedicine, University of Basel, Switzerland; Swiss Centre for Applied Human Toxicology (SCAHT), Basel, Switzerland. Electronic address: jamal.bouitbir@unibas.ch.
  • Alshaikhali A; Division of Clinical Pharmacology & Toxicology, University Hospital, Basel, Switzerland; Department of Biomedicine, University of Basel, Switzerland.
  • Panajatovic MV; Division of Clinical Pharmacology & Toxicology, University Hospital, Basel, Switzerland; Department of Biomedicine, University of Basel, Switzerland.
  • Abegg VF; Division of Clinical Pharmacology & Toxicology, University Hospital, Basel, Switzerland; Department of Biomedicine, University of Basel, Switzerland.
  • Paech F; Division of Clinical Pharmacology & Toxicology, University Hospital, Basel, Switzerland; Department of Biomedicine, University of Basel, Switzerland.
  • Krähenbühl S; Division of Clinical Pharmacology & Toxicology, University Hospital, Basel, Switzerland; Department of Biomedicine, University of Basel, Switzerland; Swiss Centre for Applied Human Toxicology (SCAHT), Basel, Switzerland.
Toxicology ; 426: 152281, 2019 10 01.
Article in En | MEDLINE | ID: mdl-31445075
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Stress / Sunitinib / Heart Diseases / Mitochondria, Heart / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Toxicology Year: 2019 Document type: Article Country of publication: Irlanda
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Stress / Sunitinib / Heart Diseases / Mitochondria, Heart / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Toxicology Year: 2019 Document type: Article Country of publication: Irlanda