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ER Stress Priming of Mitochondrial Respiratory suPERKomplex Assembly.
Quintana-Cabrera, Ruben; Soriano, Maria Eugenia.
Affiliation
  • Quintana-Cabrera R; Institute of Functional Biology and Genomics, University of Salamanca, 37007 Salamanca, Spain; Institute of Biomedical Research of Salamanca, University Hospital of Salamanca, University of Salamanca, CSIC, 37007 Salamanca, Spain; Department of Biochemistry and Molecular Biology, University of Salamanca, 37007 Salamanca, Spain; CIBERFES, Institute of Health Carlos III, 28029 Madrid, Spain.
  • Soriano ME; Department of Biology, University of Padova, Via U. Bassi 58/B, Padova 35121, Italy. Electronic address: mariaeugenia.soriano@unipd.it.
Trends Endocrinol Metab ; 30(10): 685-687, 2019 10.
Article in En | MEDLINE | ID: mdl-31455568
ABSTRACT
Assembly factors are necessary for the formation of mitochondrial supercomplexes (SCs) and in making cellular respiration more efficient. In a recent study, Balsa et al. (Mol. Cell, 2019) report that nutrient-induced endoplasmic reticulum (ER) stress engages PERK-eIF2α-mediated transcription of the SCs assembly factor SCAF1, events that coordinate ER stress and SCs formation to improve bioenergetics.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Eukaryotic Initiation Factor-2 / EIF-2 Kinase Language: En Journal: Trends Endocrinol Metab Journal subject: ENDOCRINOLOGIA / METABOLISMO Year: 2019 Document type: Article Affiliation country: España
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Eukaryotic Initiation Factor-2 / EIF-2 Kinase Language: En Journal: Trends Endocrinol Metab Journal subject: ENDOCRINOLOGIA / METABOLISMO Year: 2019 Document type: Article Affiliation country: España