Your browser doesn't support javascript.
loading
Five new polyhydroxylated furostanol saponins from the rhizomes of Tupistra chinensis.
Li, Yu-Ze; Song, Bei; Zheng, Xu-Dong; Huang, Wen-Li; Zhang, Hua-Wei; Jiang, Yi; Yue, Zheng-Gang; Song, Xiao-Mei; Liu, Jian-Li.
Affiliation
  • Li YZ; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University, Xi'an 710069, China.
  • Song B; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University, Xi'an 710069, China; Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, School of Pharmacy, Shaanxi University of Chinese
  • Zheng XD; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University, Xi'an 710069, China.
  • Huang WL; Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang 712046, China.
  • Zhang HW; Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang 712046, China.
  • Jiang Y; Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang 712046, China.
  • Yue ZG; Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang 712046, China.
  • Song XM; Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang 712046, China. Electronic address: Songxiaom@126.com.
  • Liu JL; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University, Xi'an 710069, China. Electronic address: jlliu@nwu.edu.cn.
Chin J Nat Med ; 17(8): 624-630, 2019 Aug.
Article in En | MEDLINE | ID: mdl-31472900
ABSTRACT
Five new polyhydroxylated furostanol saponins were isolated from the roots and rhizomes of Tupistra chinensis, and their structures were determined as tupistrosides J-N (1-5), together with four known furostanol saponins (6-9), on the basis of physico-chemical properties and spectral analysis. Among them, compounds 3 and 5 showed cytotoxicity against human cancer cell lines SW620 with IC50 values of 72.5 ± 2.4 and 77.3 ± 2.5 µmol·L-1, respectively. Compound 4 showed cytotoxicity against human cancer cell line HepG2 with IC50 value of 88.6 ± 2.1 µmol·L-1.
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Saponins / Sterols / Liliaceae / Antineoplastic Agents Limits: Humans Language: En Journal: Chin J Nat Med Year: 2019 Document type: Article Affiliation country: China
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Saponins / Sterols / Liliaceae / Antineoplastic Agents Limits: Humans Language: En Journal: Chin J Nat Med Year: 2019 Document type: Article Affiliation country: China