Efficacy and Safety of High-Intensity Focused Ultrasound for Noninvasive Abdominal Subcutaneous Fat Reduction.
Dermatol Surg
; 46(2): 213-219, 2020 02.
Article
in En
| MEDLINE
| ID: mdl-31490305
ABSTRACT
BACKGROUND:
Demand for noninvasive body contouring has increased.OBJECTIVE:
We evaluated the efficacy and safety of a thermal high-intensity focused ultrasound (HIFU) device for abdominal body shaping. PATIENTS ANDMETHODS:
Adults with a body mass index ≤30 kg/m and an abdominal subcutaneous fat tissue thickness ≥2.5 cm were enrolled for HIFU treatment at energy levels of 150 J/cm (first session) and 135 J/cm (second session). The primary end point was a change from baseline waist circumference at post-treatment Week 8. Secondary efficacy end points were changes in body weight, waist/hip ratio, and fat thickness assessed by ultrasound, caliper, and a fat CT scan. The Global Aesthetic Improvement Scale was evaluated by both investigators and subjects.RESULTS:
The primary assessment achieved statistical significance, showing a reduction of 3.43 cm in mean waist circumference. The treatment effect was cumulative, with a steady decrease in waist circumference and fat thickness. The mean pain scores immediately after treatment were 4.45 ± 2.74 on a scale of 1 to 10 with 10 being the most painful, which decreased to 1.10 ± 1.33 after 1 week.CONCLUSION:
High-intensity focused ultrasound is an effective and safe treatment modality for reducing waist circumference in nonobese individuals with focal fat accumulation.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Subcutaneous Fat, Abdominal
/
Obesity, Abdominal
/
High-Intensity Focused Ultrasound Ablation
/
Pain, Procedural
/
Body Contouring
Type of study:
Etiology_studies
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Dermatol Surg
Journal subject:
DERMATOLOGIA
Year:
2020
Document type:
Article