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A NeuroD1 AAV-Based Gene Therapy for Functional Brain Repair after Ischemic Injury through In Vivo Astrocyte-to-Neuron Conversion.
Chen, Yu-Chen; Ma, Ning-Xin; Pei, Zi-Fei; Wu, Zheng; Do-Monte, Fabricio H; Keefe, Susan; Yellin, Emma; Chen, Miranda S; Yin, Jiu-Chao; Lee, Grace; Minier-Toribio, Angélica; Hu, Yi; Bai, Yu-Ting; Lee, Kathryn; Quirk, Gregory J; Chen, Gong.
Affiliation
  • Chen YC; Department of Biology, Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
  • Ma NX; Department of Biology, Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
  • Pei ZF; Department of Biology, Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
  • Wu Z; Department of Biology, Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
  • Do-Monte FH; Departments of Psychiatry and Anatomy & Neurobiology, University of Puerto Rico School of Medicine, P.O. Box 365067, San Juan 00936-5067, Puerto Rico.
  • Keefe S; Department of Biology, Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
  • Yellin E; Department of Biology, Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
  • Chen MS; Department of Biology, Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
  • Yin JC; Department of Biology, Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
  • Lee G; Department of Biology, Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
  • Minier-Toribio A; Departments of Psychiatry and Anatomy & Neurobiology, University of Puerto Rico School of Medicine, P.O. Box 365067, San Juan 00936-5067, Puerto Rico.
  • Hu Y; Department of Biology, Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
  • Bai YT; Department of Biology, Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
  • Lee K; Department of Biology, Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
  • Quirk GJ; Departments of Psychiatry and Anatomy & Neurobiology, University of Puerto Rico School of Medicine, P.O. Box 365067, San Juan 00936-5067, Puerto Rico.
  • Chen G; Department of Biology, Huck Institutes of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA; Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou 510632, China. Electronic address: gongchen@psu.edu.
Mol Ther ; 28(1): 217-234, 2020 01 08.
Article in En | MEDLINE | ID: mdl-31551137
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Therapy / Brain Ischemia / Astrocytes / Basic Helix-Loop-Helix Transcription Factors / Cellular Reprogramming / Neurons Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Therapy / Brain Ischemia / Astrocytes / Basic Helix-Loop-Helix Transcription Factors / Cellular Reprogramming / Neurons Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos